Pros: 4th supermicro MB i ever owned. everything works as described....nothing to complain (which is a good thing)

Cons: NA

Other Thoughts: I purchased in Nov 2015 and the BIOS supports E5 2620 v3 directly

Pros: Yes it does, I run 2X Intel Xeon Processor E5-2699 v3 CPU's...

The 2X Intel Xeon Processor E5-2640 v3 CPU's use the same LGA2011 R3 socket.

Just make sure that the bios, and for that matter, that you install all the updates to your board before you start

Cons: no glaring problems

Pros: Runs cool, programs don't crash, stable while running.

Cons: Too slow to keep up with 4K video editing in Premiere. Playback is laggy, stutters and drops frames at random throughout playback.
Even though I have the fastest GPU that nVidia makes at this current time, the system simply can't feed it fast enough. Cinebench R15 benchmark is only 59FPS on this system. My 7 year old Core2Quad with a GTX680 scores 78FPS on this OpenGL test. The new dual Xeon machine should run circles around it, but doesn't.
The motherboard takes several minutes just to power on self-test. When Windows is ready to boot, the monitor shuts off and I cannot see anything, thus cannot use the F8 boot menu if I want to do a system restore or boot in safe mode. The on board VGA is disabled both by jumper and in the BIOS, so I don't understand where my boot screen is going because it's not on the primary or secondary monitors when starting up. These long startup cycles are responsible for troubleshooting taking many hours for just one problem. I've spent the past month troubleshooting this system with Supermicro tech support, but have yet to get any productive work done.
Once I get my monitors configured the way I need them for work (2.5K main desktop, 4K for video playout), any I make ANY change to BIOS settings, the system will scramble the monitor configuration and for the next dozen boot cycles will force some nonsense resolution of 640x480 on the 4K monitor and move the desktop there, scrambling the icons and leaving my main monitor blank and no way to function. The system worked okay until I made a tech support recommended change to CPU EIST setting in an attempt to improve performance. From that point forward, I cannot boot properly. I've never seen anything like this on any system I've built before. Even after a system image restore, the display resolution problem persists, so the problem is hardware, not software.
I've tried a couple of different NLE software on this machine, but none can play 4K 60P media at all. 4K 24P is iffy, with sometimes smooth play for a few seconds then it stops, or stutters.
In summation, there is something not right with this motherboard, or the combination of GPU and the motherboard. The erratic behavior makes it seem like possessed by demons. The fact that any simple change to BIOS causes the monitor config to go haywire is too much. But the inability to play video without constant stutters is a deal-killer.

Other Thoughts: My peers are editing these same camera files on Macbook computers with no problems, so these files apparently don't take a lot of resources to edit. Why a dual Xeon can't edit 1080 and 4K without dropping frames doesn't make sense. It must be a hardware conflict with this motherboard, otherwise big system integrators would not use them for 4K editing workstation builds costing five figures and up.
The system is stable and software doesn't crash, but performance just won't match or surpass my 7 year old Core2Quad, despite the fact that this system has 16 cores total.
Floating point performance in nBench comes in about 30% lower than my Core2Quad, which surprised me, given that I'd read that the Xeon E5 series v3 have 16X faster FP operations per clock cycle than prior CPUs.
The system is useless for the intended purpose. I've got financing payments to cover now, but no improvement in productivity to show for it. I'll have to part it out and sell the components through an online auction site and take the loss, as the cycle of tech support vassilations have run my past the RMA period.

Pros: Takes lots of memory, takes V3 Haswells, 3 pci-e x16s...

Cons: Stupidly, I didn't think of looking at the board layout before I purchased everything and now I realize that one cannot in fact install memories in the C1, C2, and D1 slots for cpu1 without having them block the Slot6 PCI-E x16 slot, which is where I was intending to install a third graphics card. Presumably I will be able to put those dimms into some other slots (against the manual's recommendation), and presumably will incur some speed cost.

Other Thoughts: I am using 2 x Xeon E5-2697 v3 and SAMSUNG 32GB DDR4 SDRAM DDR4 2133 M386A4G40DM0-CPB with this board. I had to RMA two earlier shipments of this same board, but I blame that on an EVGA power supply and/or an EVGA 970 GTX, not on the motherboards. I haven't had much trouble putting this board into an old thermaltake case, and the earlier reviewer that mentions the unrelated documentation is correct: the included diagram is for an older board, and not of much use. I haven't yet investigated his claims viz the BIOS. And you will need to get the special narrow heatsinks, as mentioned elsewhere (I bought the supermicros SNK-P0048PS, $20, here on newegg).

Pros: Don't be mislead by the first review, the BIOS is straightforward and simple. Many (like myself) use legacy mode with oboards like these because one or more component (like SAS/RAID controllers or Xeon Phi) don't properly support EFI in the first place.

Cons: The price seems a bit high for not integrating a SAS controller like they do on other models.

Other Thoughts: There is a 122 page manual located at: http://www.supermicro.com/manuals/motherboard/C606_602/MNL-1491.pdf
I admit to being frustrated with Supermicro's lack of documentation when they stopped shipping boards with manuals about two years ago, but I am used to looking them up online now.
I used 16x Crucial CT8G4RFS4213 work fine. I have yet to encounter a memory compatibility issue on this platform, so I would venture to guess

Pros: I just want to ask the brothe3r who left the first message what ram he used

Cons: none

Other Thoughts: none

Pros: Good price, good features (10 Sata3 ports, numerous PCIe ports, 16 DIMM sockets). Ultimately it's fast if you can stick with getting it configured.

Cons: BIOS Nightmare.

Has DUAL EFI / Legacy BIOS. I've used several other EFI BIOS and Legacy are old hat, but this combo set up will drive you nuts. Installed OS when set to both, decided to change to EFI, lost OS install, no apparent recovery (setting back to DUAL didn't help). In EFI mode, you never see any PCIe card ROMs post. Not so for any other EFI BIOS I've used. So far, when changing the BIOS settings, I've lost the OS and had to re-install 4 times.

Building Hyper-V server difficult. BIOS defaults allowed Hyper-V Hyper-visor to install, but performance was 2/3s what it should have been (Passmark 8 CPU index of 15K for E5-2640V3 - should have been 21-22K, RAM Speed 1400 instead of 2000). Setting CPU BIOS settings that improved CPU and RAM performance made it so the Hypervisor could not install. Additional problem turned out to be related to Intel virt-d settings. Had to enable them (all of them) when some Tech Net articles say these cannot be on.

How hard would it be to invest 4 hours to define each and every BIOS setting in the manual?

No enclosed manual. Online manual was for a different mobo (or so it seems in the inaccurate diagrams, etc).

Memory configuration information is lacking. We have choices of several DIMMs (RDIMM, UDIMM, LRDIMMs, single bank, double bank and quadruple bank) and there is no mention of any rules for what combinations can work together. No indication if we can use all 16 sockets if w're using dual or quadruple bank'd RDIMMs.

Other Thoughts: Be prepared to spend hours cycling thru combinations of BIOS settings. Run Passmark 8 and check RAM (1900-2000 for DDR4 2133) and CPU (dual Xeon E5-2640v3s should give 21000-22000 CPU score). If you don't get these results, you're not getting your money's worth.

I expected a more thorough job from SuperMicro and for a mobo over $400. Setting up a server shouldn't be this hard.