Pros: Purchased this display to upgrade from 1080p normal tv and have to say I'm impressed. I've heard many issues people were having with quality control and defects. The model I received seems to be one of the lucky ones. Currently playing anything from movies/videos, gaming, benchmarking/stress testing (system related really), and normal pc activities. Took a few minutes to calibrate using Windows 10 calibration tool though worked through it. I bought this monitor when it went on sale for 259$ and decided to pitch in the 1 year replacement plan as an added precaution. Still keeping an eye on it while working and playing. May update this later in case anything happens (knock on wood).

Cons: Tiny bezel for each side and about an inch for the bottom, nothing really concerning about it. Slight backlight bleed though only when the screen is turning on or off or displaying just a black screen though meh resolution, picture, and color for when playing or displaying anything topples the scale for that. Last thing would be the bright power indicator on the bottom right (there's a setting to turn that off). That last part wasn't really a con though it was mentioned as one in a previous review somewhere so no need to worry. Though the button mapping for the display menu were a bit confusing at first.

Other Thoughts: Setup:
Intel i7 3770K @ 4.7ghz
Asus Sabertooth Z77
Corsair Dominator 16gb Ram
Asus GTX 780 SLI (High-Ultra settings still for most games, very pleased with them)
EK custom watercooled setup

Pros: I just recently finished building a new home PC with a nice graphics card. (PNY GeForce GTX 970 4GB Rev 2) . When I saw this monitor on sale over $100 less than it normally goes for I was interested to say the least as it checked all the boxes i was looking for. IPS and 1440 were what I wanted. I did not think I would be able to touch one for under $400 but this was much less. Here are my initial thoughts after less than a day of use.

Setup was normal. Like any other monitor. Unbox, attached base, Connect height adjustable stand to monitor, plug in all cables and turn it on. My old monitor was only 1920 X 1080 but when my new PC found this monitor it auto set display resolution to 2560 X 1440.

My first thought was "WOW that is crisp, bright and vibrant". While the text is smaller than on 1920 X 1080 I have no trouble reading it and I have been using monitors for over 30 years so my eyes are not what they used to be.
Next I wanted to check for any dead pixels or screen defects. I set the screen to all white and looked and looked and ...found nothing, no dead pixels or stuck pixels. I did try the whole light bleed issue but the sun is shining bright today and even with all the blinds closed and the screen set to black it was not dark enough to judge if there was any bad light bleed. I will try again tonight and update if I find any issues.
One last note. I must live (Chicago) a few hours away from a newegg distribution center because I ordered this on a Friday and had it 24 hours later and I only paid for supersaver shipping.

Cons: So far I have no cons (unless you consider the sudden urge to buy a GTX 980ti to push this thing to its limits)

My whole experience with the monitor and newegg.com has been fantastic.

Other Thoughts: Just a few things to let others know. I have used this monitor on both my DVI and HDMI ports and have been able to set resolution to 2560 X 1440 without issue. I know others have said they had some trouble but I did not.

Pros: its a monitor

Cons: I've purchased 6 ASUS monitors over the past few years. They have ALL died. Do like I do, no matter how good of a deal it looks, don't purchase ASUS monitors. (to be clear, I'm an ASUS fan, all my mother broads are ASUS... no problems with them... but their monitors are bad)

Pros: Unbelievably crisp
Easy to rotate to portrait mode on the fly

Cons: Some quality control issues

Other Thoughts: I was lucky to grab this monitor on sale--I was unlucky that the first one I got had a weird bright spot in the middle. Not a dead pixel, a weird 1/2 inch spot that was brighter than everything around it. Never seen anything like it in a monitor before. I was able to RMA it, and the second one I got is flawless. Looks like a lot of stories of weird quality control issues in the reviews, so make sure yours is 100% before you trash the box.

The actual operation of the monitor itself is amazing. Gorgeous picture quality. Exceptionally crisp. Maybe the best feature is the stand, which allows you to convert it to portrait mode in seconds--literally with one hand. It's completely changed the way I work. If you can grab it on sale, or can wait for the price to come down, I would. If you need a good 2K monitor today, this is it.

Pros: frameless design
good color

Cons: -BAD BAD quality control, all the seven physical button only has one function, turn off the monitor, but I was told they are "settings for the monitor" all SEVEN buttons, I couldn't turn on the settings menu, I couldn't change the mode, because no matter how I push no matter which buttons on the monitor, they will turn off the monitor, or they will lock the button to disabled.

Manufacturer Response:

Dear Taoli,

Hello, I would like to thank you for taking your time in writing this review. We certainly value your feedback. It is unfortunate to hear that you are having issues with the physical buttons on your monitor. Sorry for the the inconvenience this caused you. If you didn't know, you can submit an RMA at http://www.asus.com/us/support. ASUS offers 2 to 3 year warranty on our monitors depending on the problem. If you have any questions or concerns, feel free to contact me at cl-justin@asus.com and I will help you to the best of my abilities. I'm here to assist our customers with our products and dedicated in bringing a resolution to all issues that they may come across.Your case for reference is #N160336897

Thanks for choosing ASUS

Regards,
Justin
ASUS Customer Loyalty

Pros: I bought 3 of these so this review is my thoughts on all of them together. I bought 2 on sale and one at full price.

Decent monitor for the price especially if you get it on sale like i did for the most part.
Color is nice and sharp
Unlike what alot of other reviews said mine didn't have alot of backlight bleed, mine didn't have hardly any at all on any monitor. there is 1 spot on 1 of the monitors but its not that bad.
More screen space
Very sturdy stand, when i say sturdy i mean really sturdy and doesnt move at all i if bump the desk. Very happy with it.
Able to tilt it portrait or horizontal.
Zero dead pixels on all 3 monitors.

Cons: Now on to the negatives.
Not trully bezel-less but at this price point what can you expect. not really a con but not a pro either. though i will say between 2 of these there is a half inch bezel all together between 2 monitors butted together.

Yes there was no back light bleed, but the brightness of this monitor is blinding. I have my brightness set to 20 and its still a bit bright.
The 170 degree viewing angle is a complete LIE. if your not staring straight at it from dead center your view is effected. If your off to one side even slightly the screen appears to have a grey tint and looks washed out. This can be a make it or break it for some people.
QC is utter garbage. Bottom bezel where it says asus is as wavy as the ocean. in some places its maybe a half mil from touching the screen and some places its 3 mils from the screen. it was like this on both monitors that i got on sale, but was a bit better on the full priced unit.
One of my screens appears to be missing some of the matte screen coating or its applied too thin. Two monitors are matte and doesnt reflect and the other is not. Its mostly matte but theres a few spots around the size of a quarter that reflects light just like a mirror. They almost look like smuges that dont come off.
Two of my monitors came in with the seal broken, i ordered new. maybe they broke in the mail but then again maybe not.

Other Thoughts: There are little to no other on brand 1440p monitors within the $265 price that i bought them for. So when i seen that these were on sale and in my budget i jumped on them. Im glad i did because literately a day later they were out of stock on other sites and newegg and other stores had them for huge markups. I bought 3 of them but the sale was for a max of 2. I had to buy another a few days later. knowing everything that i know about these monitors that i do now, would i buy them again. yes. They have QC issues, they dont have 170 degree viewing angles, they have a super bright screen, but that doesnt make these bad monitors. I Personally think at the $265 price that i paid for it, its a great deal, but not at the $320-350 that they are normally and that i paid for the last one. there are just too many QC problems on these to be that price. If you see them on sale however, pick them up because they go out of stock fast for a reason.

Pros: Color and viewing angles are great, as is the brightness

Cons: I've had it for about a week...maybe two...but I noticed when I had a completely white screen...there are two smudges/scrapes on the inside face of the monitor about in the middle of the screen. I've tried wiping them off but wish it would have gotten caught in QA.

And I'm not sure how to do the rapid replacement of the monitor.

Other Thoughts: I would definitely look closely at the screen when you first get it.

Pros: Zero dead pixels and no noticeable backlight bleed out of the box
Easy to assemble and very sturdy stand
Good range of presets for color balance
Stand seems very sturdy with easy height, tilt and swivel adjustment

Cons: Slow on-screen menu, takes lots of clicks to get anywhere (I'm not docking an egg because it doesn't affect my daily use of it)

Other Thoughts: This is my first time with an IPS panel, and let me tell you, I don't think I could ever go back. These colors are beautiful and the image is nice and sharp thanks to the high resolution.
I'm not sure whether I will ever find it useful, but the ruler marks along the bottom bezel of this monitor are a bit odd. I get their purpose, but I have a hard time believing there is enough market for a feature like that.
Right out of the box I turned the brightness down to 50% and switched it to Gaming mode for color balance, it was amazingly bright out of the box even at only 75%, and I like the Gaming balance better than the default, but your mileage may vary. I was also noticing some eye strain part way through the first day as I spend a lot of time at my computer, but after turning on the blue light filter setting, I haven't had any issues.
My only warning is about the size. This monitor is fairly small as 1440p displays go, but after getting it set up on my desk, I noticed that thanks to the large base and large display (my old one was 21") it now feels almost uncomfortably close if I sit how I used to. Over the last week I have noticed myself leaning back in my chair much more.

Pros: Everything looks crisper and clearer
Used to think my favorite game had mediocre graphics even at maximum settings with my old monitor (1680x1050 resolution)
now seeing it at 2560x1440 it's obvious what I was missing.

Was on sale when I bought it.

Cons: none

Pros: -Little to no backlight bleed on this specific unit.
-Colors look great.
-Stand is sturdy like my PB278Q

Cons: About 5 specks of dirt in the middle of the screen

Other Thoughts: I am hesitant whether to return this monitor or not. While there is no backlight bleed, I have five specks of dirt in the middle of the screen. They aren't dead pixels which some people may be referring to the as, but it's just as bad. On a side note my PB278Q also had this problem but it was around the edges of the screen, not in the main viewing area.