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Item#: N82E16813130567

MSI E350IS-E45 AMD E-350 APU (1.6GHz, Dual-Core) AMD Hudson M1 Mini ITX Motherboard/CPU Combo

  • AMD E-350 APU (1.6GHz, Dual-Core)
  • AMD Hudson M1
  • 2×240pin DDR3 1066/1333 (OC)
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Learn more about the MSI E350IS-E45


Combo Type
Motherboard/CPU Combo


AMD E-350 APU (1.6GHz, Dual-Core)
With Cooler

Supported CPU

CPU Type


North Bridge
AMD Hudson M1


Number of Memory Slots
Memory Standard
DDR3 1066/1333 (OC)
Maximum Memory Supported

Expansion Slots

PCI Express x16
1 x PCI Express x16 slot with x4 operation (PCI Express Bus SPEC V2.0 compliant)

Storage Devices

4 x SATA 6.0Gb/s

Onboard Audio

Audio Chipset
Realtek ALC887
Audio Channels
8 Channels

Onboard LAN

LAN Chipset
Realtek 8111E
Max LAN Speed

Rear Panel Ports

1 x PS/2 keyboard or mouse
Video Ports
1 x HDMI
USB 1.1/2.0
6 x USB 2.0
1 x Optical, 1 x Coaxial
Audio Ports
3 Ports

Internal I/O Connectors

Onboard USB
4 x USB 2.0

Physical Spec

Form Factor
Mini ITX
6.7" x 6.7"


All Solid Capacitors

Winki 3



Live Update 5


Manufacturer Warranty

3 years limited
3 years limited

Quick Info


  • Limited Warranty period (parts): 3 years
  • Limited Warranty period (labor): 3 years

Customer Reviews of the MSI E350IS-E45

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  • Jared T.
  • 3/3/2013 9:34:58 PM
  • Tech Level: High
  • Ownership: 1 month to 1 year
  • Verified Owner

5 out of 5 eggsFast low power little motherboard

Pros: Pretty quick for how little power it uses. I'm using it as an HTPC and will migrate it to a carputer in a tiny case.

Cons: needs 24 pin atx and cpu power plug while a lot of micro atx psu's and such don't have those features. Not hard to make it work though, I can barely call this a con!

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  • Sarah L.
  • 4/13/2012 11:57:12 AM
  • Tech Level: Somewhat High
  • Ownership: 1 month to 1 year

4 out of 5 eggsGreat for a low-wattage NAS/development box!

Pros: When the BIOS failed on an old 3.06GHz P4 system I was using as a Linux development box, I racked my brain trying to decide on replacing the board or purchasing something new. I'm so glad I chose to upgrade!

I was worried that I would lose the heavy-lifting of the old-school, big-wattage P4 for the various VMs I use daily, but going to a dual-core, 1.6GHz, 64bit AMD Zacate system has made most of those thoughts disappear. For one thing, I went from maxing out the old machine with 2GB of DDR to maxing this board with 8GB of DDR3. Only one Mini-ITX Atom board sold by Newegg supports more than 4GB.

Not only can I run multiple VMs at the same time w/ VirtualBox, I can also at the same time run FreeNAS in a VM with direct access to two SATA drives for my media needs. And the best thing? I've gone from using on average ~135w to <30w total!

Cons: Only thing that's an actual hassle right now is with Wake-on-LAN (WOL), which for some reason isn't triggering when I send the Magic Packet. It'll wake on USB and the settings all match up, but it just won't WOL. Reading the MSI forums, apparently this is a problem for a number of people. Then again, at <30w I'm not dying to turn it off...

The other goofy thing is a weird requirement to be running Windows in order to apply the newest BIOS update. Although there is a place in the BIOS to update through a USB drive, the MSI instructions insist that using any other method than Windows will corrupt it.

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  • Michael T.
  • 3/10/2012 10:37:24 AM
  • Tech Level: High
  • Ownership: 1 day to 1 week
  • Verified Owner

5 out of 5 eggsGreat

Pros: Works as expected, used in a HTPC mini-itx build and fits in great and makes the HTPC fly!

I chose this because it offers not only optical for S/PDIF but also coax which is really stupid that not every motherboard today for media use doesn't include both.

Cons: None, has everything I needed and more

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  • Chad M.
  • 3/8/2012 6:55:18 AM
  • Tech Level: Somewhat High
  • Ownership: 1 day to 1 week
  • Verified Owner

5 out of 5 eggsGreat little server motherboard.

Pros: Fast, solid right out of the box, easy to install. Looks and feels like a quality board. Loaded OS with flash drive, so no need for DVD ROM. 4 SATA headers, HDMI, Toslink and gigabit ethernet.

Cons: No case speaker header. Fan is a little loud but can be silenced with a tweak in the BIOS.

Other Thoughts: Popped this little mobo in a APEX MJ-16 case and it booted right up. I used 4 GB of G.SKILL Ripjaws Series 240-Pin DDR3 SDRAM DDR3 1066 RAM. Installed OS with flash drive by telling the BIOS to boot the USB first. Windows Home Server had all the drivers except the LAN, so I had to install that from flash drive. I also installed the video card driver downloaded from MSI website. I haven't put ATI's CCC on there since it's just a server and will be running the unit headless. I already had the hard drives, so I was able to build a small home server for about $150. Can't beat that!

1 out of 1 people found this review helpful. Did you? Yes No

  • Albert A.
  • 2/17/2012 4:24:28 PM
  • Tech Level: Somewhat High
  • Ownership: 1 week to 1 month
  • Verified Owner

5 out of 5 eggsCheap, small, quiet

Pros: Perfect for HTPC, browsing, email, small server. SATA III, gigabit LAN. Great deal with rebate, good deal even without it.

Cons: Missing some extras like USB 3, but no real cons considering the cost.

Other Thoughts: Booted right up with two different sets of 2x4GB 1300-rated RAM. Don't know why the other reviewer had trouble.

Flash Player version 11.1 drops frames/stutters even with hardware acceleration. Dropping back to version 10.3 works much better. Have the same issue with another computer, so it's not this board that's the problem.

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  • Jason B.
  • 1/27/2012 11:51:47 AM
  • Tech Level: High
  • Ownership: 1 week to 1 month
  • Verified Owner

3 out of 5 eggsBad product description

Pros: Small, efficient, somewhat quiet. Powerful enough for HTPC.

Cons: Very poor product description lead me to try and build a system using this board and 1333Mhz DDR3. The manual clearly states it supports 1066Mhz DDR3 ONLY.

Newegg's fecally-infused description contains:

DDR3 1066/1333 (OC)

Which is fine if you know to interpret this as "Supports DDR3 1066Mhz RAM that can then be overclocked TO 1333Mhz."

To me, that says "It supports 1066Mhz, 1333Mhz, and can be overclocked."

Other Thoughts: I've been building systems for 17 years, and I was easily able to identify the reason the system wouldn't boot with 1333Mhz DDR3 installed, but will everyone?? How much hassle could be saved by spending 15 seconds and writing 10 more words on the RAM supported.

3 out of 13 people found this review helpful. Did you? Yes No

  • David B.
  • 1/6/2012 7:07:50 AM
  • Tech Level: High
  • Ownership: 1 day to 1 week

4 out of 5 eggs

Pros: Works fine.

Cons: A little slow for computational needs if you're used to Sandy Bridge speed.

Other Thoughts: The fan quiets down if you update the BIOS. I found the BIOS fan control didn't work until I updated to the current BIOS. Right after the reboot following the BIOS update, I could hear the fan quiet down.

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  • Michael C.
  • 12/25/2011 9:31:16 PM
  • Tech Level: High
  • Ownership: 1 week to 1 month
  • Verified Owner

4 out of 5 eggsGreat Price for a Great HTPC Board/CPU Combo

Pros: The E-350 APU, Very nice little APU. Runnning Win7 64 Pro with 4 gig 1333 and 3.5" 500 GB WD Black Label Drive which is working fantastic for a "HD DVR" HTPC with a Dual Tuner.

The E-350 handles all media with no issues except one format (See Cons) H264 at 1080 with subs play flawlessly at around 35-40% usage with DXVA configured in MPC. Media Center records 2 programs at once from a cheap usb tuner at 15% usage and can watch and record with around 60% usage.

Youtube plays smooth at 1080 with no studdering or droped frames as does Netflix and any other online streaming site.

coretemp is logging my system at around 41C Idle and 62C Full. Not bad as it is in a large Cabinet with bad ventilation and a 800 Watt Receiver. TDP is 95C and feel fine running it into the 70's with out a worry in the summer.

Cons: The Fan is very loud and detracts from a HTPC or any environment. (Adjustable in Bios which does help if you want to play with higher temps)

Will not play 10 Bit H264 MKVs in either 1080 or 720 smoothly. This is a very new format which is not DXVA compatible so needs raw processor power which the 350 can't handle.

Other Thoughts: Solid Mini Itx board with an excellent set of outputs that allow perfect hookup to a Home Theater System just as I want that will play bacl nearly all your media with ease.

1 out of 1 people found this review helpful. Did you? Yes No

  • Joshua T.
  • 12/13/2011 7:31:03 AM
  • Tech Level: High
  • Ownership: 1 week to 1 month
  • Verified Owner

4 out of 5 eggsSo far so good.

Pros: Running fine so far, was easy to set up in the Rosewill mini-itx case I picked up for it. 8GB ram and Win7 64bit runs fine.

Cons: A little on the slow side, to be expected though due to the cpu speed. CPU fan was loud, I swapped it out with a 80mm fan that now blows on the little cpu heatsink and the chipset heatsink. The CPU heatsink should be bigger for sure, even with the fan swap and better airflow the temps stay at 50C when idling on the bios screen. So far I have not been able to find any software to show the CPU temp sensor output while in Windows.

Other Thoughts: So far I have only tested with non-hd Netflix streaming. My plan is to also test with XBMC streaming across network from my local server, also need to test Netflix HD content.

1 out of 1 people found this review helpful. Did you? Yes No

  • Justin B.
  • 12/9/2011 4:18:24 PM
  • Tech Level: High
  • Ownership: 1 week to 1 month
  • Verified Owner

4 out of 5 eggsDecent little board

Pros: Small footprint, good specs, smooth install.

Cons: No Case Speaker output.

Other Thoughts: Very nice all-in-one. The only downside is that there is no connection for a case speaker. It runs Win 7 Ultimate x64 flawlessly and surprisingly well considering the CPU Power.

Did you find this review helpful? Yes No

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MSI > 
Item#: N82E16813130567
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