Pros: To get these installed all I did was load a new windows 7 64bit OS and do all the OS updates before any driver installs. Recognized just fine. Couldn't get the card to work any other way with any other drivers mentioned in the comments below.

Cons: I got the OS to recognize the ports but couldn't ever get any peripheral to be recognized connected to any of the COM ports. I rechecked everything I could.

Other Thoughts: I ended up going to a cheap USB to serial solution.

Pros: Works great. Instead of following protocol on a new build and installing drivers then installing OS updates do the opposite. After OS updates installed they are all there for the most part. I had to go into device manager and right click on an unknown device and update the driver searching via updates for one of them.
I am putting these cards into 20 Point of Sale register builds in the near future if all goes well with this initial 1 month test. So much better then a USB to Serial solution. I am hoping it is dependable through the years. These will be put to the test in my builds!

Cons: At first I tried all the drivers from V1.0 to V1.2 from their website. I then went off and searched for the Syba SD-PEX15022 2 connector drivers and They actually worked if I searched for the drivers myself through update driver in device manager. I reinstalled the OS from some messups with other things and decided to let the OS with all updates try and figure it out these Serial connections which it did after the first 50 OS updates.

Other Thoughts: I will report back if anything happens. If no report than you can safely say I am happy and all is working well with no hiccups.