Is this compatible with AMD-based systems? My laptop has a Ryzen 9 5900HX Processor

No, this wireless adapter is only compatible with 12th+ Gen Intel CPU-based laptops. It is not compatible with AMD-based systems.

Questions & Answers: Intel AX411 Double Connect WiFi 6E (Gig+) CNVio2 Tri Band 2.4/5/6GHz Wireless Adapter AX411NGW 802.11ax 2.4Gbps Bluetooth 5.3 No vPro

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Intel AX411 Double Connect WiFi 6E (Gig+) CNVio2 Tri Band 2.4/5/6GHz Wireless Adapter AX411NGW 802.11ax 2.4Gbps Bluetooth 5.3 No vPro

Ultimate Wi-Fi: Compatible with Intel Dual Connect technology--Wi-Fi using two radios simultaneously operating on the 2.4GHz and either the 5GHz or 6GHz band, respectively, for the ultimate gaming or high-performance experience
2nd Gen CRF (Companion RF): Even better than the AX201 and AX211! The AX411 has all the features you love, such as MU-MIMO, 1024QAM, OFDMA, 160MHz channels and WPA3 available in the less congested 6GHz band
Update your Wi-Fi to Tri-Band: Max Speeds up to 2.4Gbps across the 2.4GHz, 5GHz, and 6GHz bands. The 2.4GHz for long range, 5GHz & 6GHz for high speed, interference free and Ultra-low Latency Wi-Fi
WARNING!! WARNING!! WARNING!! ONLY compatible with 12th+ Gen Intel CPU-based LAPTOPS. No DESKTOP systems. REQUIRES: Linux or Windows 10/11 64-bit systems, with CNVio2 interface PC must have available M2 Slot with Key E. Suitable to replace AX201 or AX211 ONLY--AS LONG AS YOUR SYSTEM MEETS ALL OTHER REQUIREMENTS.