You can use NVME SSD with this adapter without M. 2 slot on the motherboard. Supports PCIe Gen4/Gen3 and PCIe Gen2 M. 2 NGFF 80mm, 60mm, 42mm SSD. Come with heat sink and thermal pad, can realize NVME SSD's full potential of its high performance. Support Windows XP / 7 / 8 / 10, No driver required. Only Support M. 2 NVME SSD (Key M), DO NOT support M. 2 SATA SSD (Key B). If you would like to use NVME M. 2 SSD as boot drive, please confirm your motherboard wit CSM function before buying.