This might be a silly question, but will this work with regular 4-pin RGB headers? I ask because it's advertising Aura RGB which I know nothing about.

Yes, it should work with any 4 pin RGB header. Aura is just the name of software by ASUS.

Questions & Answers: Enlabs 12V 4-Pin RGB 3-Way Female to x Female RBW LED Strip Splitter Cable,3 Port AURA RGB Lighting Hub w/ Gender Changer Adapter - 1 Foot

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Enlabs 12V 4-Pin RGB 3-Way Female to x Female RBW LED Strip Splitter Cable,3 Port AURA RGB Lighting Hub w/ Gender Changer Adapter - 1 Foot