Can this power supply handle high-end graphics cards with the PCIe 5.0 support, and does it come with the necessary cables?

Yes, this power supply includes the PCIe 5.0 / Gen 5 12VHPWR PSU connector to deliver power to the most advanced PCIe 5.0 high end graphics cards.

Questions & Answers: Apevia Prestige ATX-PR850W PCIE5.0 - Power supply (internal) - ATX12V 2.3 - 80 PLUS Gold - AC 115-230 V - 850 Watt - active PFC - cosmic black

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Apevia Prestige ATX-PR850W PCIE5.0 - Power supply (internal) - ATX12V 2.3 - 80 PLUS Gold - AC 115-230 V - 850 Watt - active PFC - cosmic black

Device Type : Power supply - active Power Factor Correction (PFC) - internal
Specification Compliance : ATX12V 2.3
PSU Form Factor : ATX
Color : Cosmic black
Cooling System : 135 mm fan
Features : Metal housing, overvoltage protection, overpower protection, short-circuit protection, single 12V rail
Compliant Standards : FCC, RoHS