Is unit compatible with Gateway DX4860-UR31P DESKTOP? How does it connect inside the computer?

It depends on the size of your case. It uses a peripheral power connector to power the adapter that then powers the 2 lights

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BYTECC UFE-421 3.5" USB3.0/Firewire 400/POWER e-SATA Combo Internal HUB

Specs

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Model
Brand	BYTECC
Model	UFE-421

Details
Types	Drive Accessories
Specifications	4 x USB 3.0 ports 2 x FireWire 400 (1 x 4pin & 1 x 6pin) 1 x Power e-SATA for USB/eSata or Power e-Sata devices Total 7 additional ports System Requirement: Windows XP or higher

Features
Features	Direct refitting to the fast USB 3.0 standard. Even with the 2 Firewire 400 connectors, it's possible to use like camcorders, hard disks or other Firewire devices. For external HDDs or Blu-ray burners the POWER e-Sata connector can help. All e-Sata devices' plug and sockets fits in the POWER e-Sata socket. Operating Power e-Sata HDDs, Drives & docking stations without their own power supply is possible with this unit.

Additional Information
First Listed on Newegg	July 06, 2011