Is this case suitable for a Mini-ITX build?

Yes, this case is suitable for a Mini-ITX build.

Can I fit a large video card in this case?

Yes, the case supports GPUs with a maximum length of 360 mm.

Questions & Answers: Thermaltake TR100 Black Computer Case CA-11A-00S1NN-00

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Thermaltake TR100 SFF Chassis mITX Support 18.9 Liters PCIe 4.0 Riser Cable Included 360mm GPU Clearance 280mm Radiator Support Removable PCIe Bracket, Black, CA-11A-00S1NN-00

Perfect for Home or Travel: Built to be portable and compact the TR100 does a great job with providing a small footprint at home and perfect for travel.
mITX Engineered: Coming in at 18.9 liters and optimized for mITX SFF builds with its dual chamber design to provide plenty of options for components.
Tiny but Mighty: While coming in at a small size, space for components is pretty roomy at 360mm GPU clearance, 280mm Raditator support, SFX and SFX-L PSU support, and 68mm of CPU cooler clearance.
PCIe 4.0 Riser: The TR100 comes with an included PCIe 4.0 Riser cable to meet the demands of modern GPUs bandwidth requirements and to faciliate easy installation.
Removable PCIe Bracket: Featuring a removable PCIe bracket for straight forward GPU installation, not to mention an integrated GPU brace for added security.

$139^.99 –