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FOR GX270 Medium Board 865 Main Board CG566 H1105 H1489 FG011
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FOR 7010SFF 9010SFF Main Board GXM1W WR7PY Q75 3rd Generation
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Compatible with GS66, WS66, 11UG, MS-16V4, BS5005HS-U4Q (16V4-CPU), and BS5005HS-U3J (16V4-G-CW).
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FOR 7551 7551G 09929-1 48.4 01 MBBKN01001 JE70-DN Main Board
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FOR S4040 1150-pin CPU Integrated Graphics Card Main Board 5B20G759
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X10DRI Dual X99 2011-3 main board C612 chipset supports E5 V3/V4 server DDR4
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FOR 790 990DT MT T1600 Workstation Main Board 6NWYK C206 Chip 98XWC
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FOR 400G3 SFF Main Board MS-7A02 V: 1.0 798930-001 799156-001
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FOR 8100 Z200 SFF Main Board MS-7557 VER2.0 531991-001 599369-001
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FOR 5320M Main Board 642740-001 646949-001 618821-001 Version Number: LA-6161P
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FOR 3330 3380 3381MT Main Board 694617-001 660512-001 702644-001
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FOR 15-BA Main Board LA-D712P LA-D713P 854969 854958 902570-001
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FOR Z230 SFF Z240SFF Main Board 698114-001/601 795003-001 837345
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FOR 800 G2 880 G2 SFF TWR Main Board 795970-002/001 795206-002/001
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FOR 600G2 680G2 SFF TWR main board 795971-001/601 795231-001
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FOR 14-AB Main Board 810972-501/001 816205-501 Version Number: DA0X22MB6D0
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FOR TPN-I120 14-AN Main Board 858043-001 Version Number: 6050A2822801 A6
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FOR TPN-I120 14-AN 245 G5 Main Board 858043-001 Version Number: 6050A2822801
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FOR 600G3 680G3 MT Main Board 911990-001 901195-001 Six or Seven Generations
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FOR 640 G4 L09565-001 L09569 6050A2930101 L09569-001 Main Board
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FOR 680 600G1 Q85 Main Board SFF795972-001 696549-003 739682-001
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FOR 340/348 G7 6050A3126701-MB-A01 L81422-601,001 Main Board
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FOR 15-AF Main Board 813967-601 818060-601 Version Number: LA-C781P A6-6310
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FOR 583079-001 4410S 4510S Main Board 583078-001 6050A2297401
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FOR TPN-I132 14-CM 245 G7 Main Board L23393-601 Version Number: 6050A2983601
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FOR 800 880 G1 SFF TWR Main Board 696538-003 737728-001 717372-003
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FOR Fo R 430 G2 Main Board 800442-601 798060-601 Version Number: LA-B171P SR23Z
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FOR D5005 E5005 M3300 B3300 Main Board LKBNM1 V: 1.0 KBY3-LT2
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FOR 650 640 G1 Main Board 744008-001 744008-601 Version Number: 6050A2566402
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FOR 800 880 G1 TWR Main Board 737727-001 696538-002 737727-501
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FOR ProOne 400 G1 Main Board COTTON 737339-001 737182 737184-00
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FOR CQ42 CQ62 Main Board 592809 592808 623915-001 DA0AX2MB6E1
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FOR 8440P 8540W 8540P HSTNN-C73C LA-4951P LA-4891P main board
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FOR 3050 MT 16510-01 Main Board VJ40T Y4H34 W0CHX DW5KY P03DX
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FOR 7020 MT 9020 MT T1700 T20 XE2 Main Board F5C5X 8WKV3 M5HN1
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Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

Anonymous
11/12/2025 7:31:12 AM
Great Epyc motherboard

“ I would recommend this MB for a small Epyc server build (nice ATX size). ”

Supermicro Server Motherboard MBD-H13SSL-NT, Socket SP5 AMD 4th Gen EPYC™ 9004/9005, Up to 3TB 3DS ECC RDIMM DDR5, ATX. Support of "EPYC 5th Gen 9005 Series"
Dgunnell
10/21/2025 7:12:25 AM
Nice server motherboard

“ I would recommend this motherboard for a home based or small business server ”

ASRock Rack Server Motherboard EC266D2I Mini-ITX 2x 1GLan Single Socket (LGA 1700) Intel Xeon E-2400 series
John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP
RICHARD B.
8/18/2025 5:25:53 AM
Doing GREAT so far (updated 1 wek in)

“ I would definitely recommend this board for your server build. ”

ASRock Rack Server Motherboard B650D4U3-2L2Q/BCM Micro-ATX AMD EPYC™ 4004/4005 and AMD Ryzen™ 9000/8000/7000 Series Dual SFP28 (25GbE)
Anonymous
7/16/2025 11:50:37 AM
Epyc 4005 worked after bios update

“ Plenty of pcie lanes for small businesses or home lab I would still recommend this board to start with, as you can always use the two other pcie lanes for expansions and leave the full 16x for a GPU or whatnot. ”

ASRock Rack B650D4U-2L2T/BCM Micro-ATX Server Motherboard Single Socket AMD EPYC™ 4005/4004 and AMD Ryzen™ 9000/8000/7000 Series Processors (LGA 1718) B650E PCIe 5.0 Dual 10G Lan
Ryland P.
6/13/2025 9:24:32 AM
SFF server board crammed with features

“ Tons of features peculiar to server boards but in a SFF ”

Supermicro MBD-X13SCL-IF-O Intel LGA-1700 Single Socket Mini-ITX Server Motherboard
Anonymous
4/15/2025 10:18:04 AM
Perfect for a server

“ Overall a great choice for a server platform using Ryzen AM5 CPUs rather than EPYC or Xeon while getting mostly the same management features. ”

ASRock Rack B650D4U-2L2T/BCM Micro-ATX Server Motherboard Single Socket AMD EPYC™ 4005/4004 and AMD Ryzen™ 9000/8000/7000 Series Processors (LGA 1718) B650E PCIe 5.0 Dual 10G Lan