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E49AL E49A E49G E49L E4430A E4430G main board
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E49AL E49A E49G E49L E4430A E4430G main board

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V480 B480 B490 M490 CF03 B4400 B5400 Main Board
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V480 B480 B490 M490 CF03 B4400 B5400 Main Board

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22-C L03377-002 DAN97BMB6E0 N97B Main Board
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22-C L03377-002 DAN97BMB6E0 N97B Main Board

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300E4A 300E4X 300E43 300E4C 3430EX 3430EA main board
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300E4A 300E4X 300E43 300E4C 3430EX 3430EA main board

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X131E E130 E10 E125 X100E X121E E120 main board
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X131E E130 E10 E125 X100E X121E E120 main board

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TPC-Q028 20-C L03379-001 L03379-602 DAN91GMB6D0 Main Board
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TPC-Q028 20-C L03379-001 L03379-602 DAN91GMB6D0 Main Board

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0R462V DAZ40 LA-F322P E7490 Main Board 0KGYDF
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0R462V DAZ40 LA-F322P E7490 Main Board 0KGYDF

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710-14 Main Board 700S-14ISK Main Board LA-D471P 710-14IKB
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710-14 Main Board 700S-14ISK Main Board LA-D471P 710-14IKB

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802518-001 850 840 G1 main board 6050A2559101
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802518-001 850 840 G1 main board 6050A2559101

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7060 7070 MT Main Board K5F13 NRKPK 17509-1 17509-3
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7060 7070 MT Main Board K5F13 NRKPK 17509-1 17509-3

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SC430 SC440 Main Board M9873 NY776 YH299
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SC430 SC440 Main Board M9873 NY776 YH299

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JW 8600H 8600T D8700T D8780T S1 3865H 7110H Main Board
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JW 8600H 8600T D8700T D8780T S1 3865H 7110H Main Board

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DC7700 DX7300 MT Main Board 404673-001 404676-001
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DC7700 DX7300 MT Main Board 404673-001 404676-001

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X2 Detachable 12-E DA0D98MBAH0 L05122-001 Main Board
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X2 Detachable 12-E DA0D98MBAH0 L05122-001 Main Board

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3060 SFF Main Board 4Y8V0 WHW95 3NH87
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3060 SFF Main Board 4Y8V0 WHW95 3NH87

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01HY149 LA-E291P 270 Main Board
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01HY149 LA-E291P 270 Main Board

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800 880 G5 TWR L65198-001/601 L61703 L37492-001 Main Board
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800 880 G5 TWR L65198-001/601 L61703 L37492-001 Main Board

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5B21B85197 NM-D471 3-14ITL6 3-15ITL6 main board
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5B21B85197 NM-D471 3-14ITL6 3-15ITL6 main board

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600 G2 SFF Main Board 795231-001 795971-001 601
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600 G2 SFF Main Board 795231-001 795971-001 601

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17-BY main board L87451-601 6050A3168901 6050A3107701
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17-BY main board L87451-601 6050A3168901 6050A3107701

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01EP403 E570 CE570 Main Board NM-A831
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01EP403 E570 CE570 Main Board NM-A831

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NM-C091 L340-15IWL Main Board
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NM-C091 L340-15IWL Main Board

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S145-15IWL Main Board NM-C121
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S145-15IWL Main Board NM-C121

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14-CF Main Board L48651-601 L38212-601 6050A3155301
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14-CF Main Board L48651-601 L38212-601 6050A3155301

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Desk 705 G2 DM Main Board 810662-003 801774 801776-001
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Desk 705 G2 DM Main Board 810662-003 801774 801776-001

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282 Pro G6 290 G4 MT L90453-001/601 L75370-001 Main Board
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282 Pro G6 290 G4 MT L90453-001/601 L75370-001 Main Board

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400 480 G5 MT Main Board L04746-001/601 L02442-021
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400 480 G5 MT Main Board L04746-001/601 L02442-021

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7000-28ICBR 7000-28ICB Main Board 17541-1 LY530 IB360CW
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7000-28ICBR 7000-28ICB Main Board 17541-1 LY530 IB360CW

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IPJ52 LA-M041P N08746-601 250 G9 Main Board
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IPJ52 LA-M041P N08746-601 250 G9 Main Board

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400 G6 SFF TPC-P066-SF L64712-001, 601 Main Board
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400 G6 SFF TPC-P066-SF L64712-001, 601 Main Board

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400 480 G5 MT Main Board L04745-001/601 L02439-021
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400 480 G5 MT Main Board L04745-001/601 L02439-021

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400 480 G4 MT SFF Main Board 911987-001 911986-001
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400 480 G4 MT SFF Main Board 911987-001 911986-001

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NP550XTA Main Board BA92-18880A BA92-18880B BA41-02660A
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NP550XTA Main Board BA92-18880A BA92-18880B BA41-02660A

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15-AB 17-G Main Board DAX12AMB6D0 X12
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15-AB 17-G Main Board DAX12AMB6D0 X12

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300-15IBR 320-14IBR main board NM-A471 NM-B301
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300-15IBR 320-14IBR main board NM-A471 NM-B301

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400G6 DM Mini Main Board L79220-002 M87688-001 601
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400G6 DM Mini Main Board L79220-002 M87688-001 601

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Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP
Anonymous
7/22/2025 11:44:14 AM
Received v1.1 (sticker) version

“ this is the 3rd AsRock Rack mobo I have owned and its great as always. the IPMI is fantastic and worked great. ”

GIGABYTE MW34-SP0 Motherboard - 14th/13th/12th Gen Intel® Core™ - ATX UP
Anonymous
5/31/2024 4:55:24 AM
The negative reviews on this board are non-sense

“ this is one of the few only server boards that has built in 10G. ”

ASRock Rack B650D4U-2L2T/BCM Micro-ATX Server Motherboard Single Socket AMD EPYC™ 4005/4004 and AMD Ryzen™ 9000/8000/7000 Series Processors (LGA 1718) B650E PCIe 5.0 Dual 10G Lan
Mark T.
12/9/2023 10:26:28 AM
Outstanding Motherboard for AM5 and has 24 PCIe lanes

“ This is a fantastic server motherboard, it has IPMI and only requires three power connections. ”

AsRock Rack B650D4U Micro-ATX Server Motherboard Single Socket AMD EPYC™ 4005/4004 and AMD Ryzen™ 9000/8000/7000 series Processors (LGA 1718) B650E PCIe 5.0 Dual 1G Lan