Skip to main content
  • In Stock
  • Sold by Newegg
  • Make an Offer
  • New
  • Combo Deals Only
Brands
Show More
Price
Show More
CPU Socket Type
North Bridge
Show More
Additional SATA RAID
Number of DDR Slots
DDR Standard
CPU Type
Show More
Number of DDR2 Slots
DDR2 Standard
Sold by
Number of DDR3 Slots
DDR3 Standard
Maximum Memory Supported
ECC Supported
Registered
Number of DDR4 Slots
DDR4 Standard
PCI Express x16
PCI Express x1
PCI Express 5.0 x16
PCI Express 4.0 x16
PCI Express 3.0 x16
PCI Express 2.0 x16
PCI Slots
SATA
SATA RAID
Additional SATA
SCSI
Onboard Video Chipset
Audio Channels
Max LAN Speed
USB 1.1/2.0
IEEE 1394
Form Factor
USB 3.0
Memory Slots
Memory Standard
M.2
All Top Brands
Availability
Condition
Current Promotion
Discount
Useful Links
Customer Ratings
  • NVIDIA AI SUPERCOMPUTE
  • Stay ahead & transform your business today
  • AMD 4005 EPYC
  • ABS Workstations, Built for Real Work
Sort By:
View:
For S5217 S5217G2 PN: 45093193 Device main motherboard
Quick View
  •  
  • $499.00 
  • $5.00 Shipping
For IH81M H81M M4500 B4550 main motherboard 00KT289 00KT266
Quick View
  •  
  • $220.00 
  • $5.00 Shipping
For BBM-LX800 machine main motherboard
Quick View
  •  
  • $574.00 
  • $5.00 Shipping
For   460-A 260A A6-7310   Mini ITX Motherboard 844844-004
Quick View
  •  
  • $218.90 
  • $15.00 Shipping
For   Dimension 5100 5150 motherboard HJ054 WG261
Quick View
  •  
  • $86.90 
  • $15.00 Shipping
For   IQ1X0MS Q170 motherboard   M8600t M8600s M6600
Quick View
  •  
  • $174.90 
  • $15.00 Shipping
For     H11H4-AI H11H4-AD motherboard H110 B430   X4650
Quick View
  •  
  • $174.90 
  • $15.00 Shipping
For  micro X10DRD-INT Dual DDR4 Motherboard NVME
Quick View
  •  
  • $768.90 
  • $15.00 Shipping
For   H110M-DS2V Supports 1151 Pin DDR3 Memory Motherboard
Quick View
  •  
  • $163.90 
  • $15.00 Shipping
For   GA-H81N 1150 pin H81 Mini Motherboard 17 * 17
Quick View
  •  
  • $218.90 
  • $15.00 Shipping
For   Z8PE-D12 1366-pin Dual Channel Server Motherboard
Quick View
  •  
  • $284.90 
  • $5.00 Shipping
For     H110D4 -M1 M2 DDR4 memory 1151 pin H110 motherboard
Quick View
  •  
  • $163.90 
  • $15.00 Shipping
For MS-7776 VER: 1.0 Motherboard H81 1150 Pin DDR3
Quick View
  •  
  • $163.90 
  • $15.00 Shipping
For       H61H2-AM V1.1 1155-pin motherboard DDR3 32 nm
Quick View
  •  
  • $119.90 
  • $5.00 Shipping
For   GA-6TXSL-RH Workstation Motherboard X58 1366 Pin
Quick View
  •  
  • $218.90 
  • $15.00 Shipping
For   AM4 854902-001 Mini Motherboard 15130-SD
Quick View
  •  
  • $218.90 
  • $15.00 Shipping
For  S4985G3NR Opteron 1207 Dawn 4-way   Motherboard
Quick View
  •  
  • $658.90 
  • $5.00 Shipping
For   GA-X58A-UD3R Motherboard X58 1366 Pin X5650 I7 960
Quick View
  •  
  • $218.90 
  • $15.00 Shipping
For   3040M 7040M motherboard MFF ITX 77RRV MGK50 96JG8
Quick View
  •  
  • $196.90 
  • $5.00 Shipping
For   IPIEL-LA3 533234-001 G43 DDR3 motherboard 583365-001
Quick View
  •  
  • $97.90 
  • $5.00 Shipping
For B250-N motherboard B250 chipset 1151 interface
Quick View
  •  
  • $218.90 
  • $15.00 Shipping
For D946GZIS distribution CPU memory spot motherboard
Quick View
  •  
  • $117.00 
  • $15.00 Shipping
For   GA-7PCSLD motherboard 1356-pin SAS SATA
Quick View
  •  
  • $306.90 
  • $5.00 Shipping
For Suoermicro X10SLQ 1150 Pin Workstation Motherboard E3
Quick View
  •  
  • $658.90 
  • $15.00 Shipping
For R3F Rampage III Formula x58 Motherboard 1366 Pin
Quick View
  •  
  • $482.90 
  • $15.00 Shipping
For X8SAX 1366 Pin Motherboard 55 56 I7-950
Quick View
  •  
  • $768.90 
  • $15.00 Shipping
For   NF560D2 Server  micro X7QC3 X7QCE Main Board
Quick View
  •  
  • $768.90 
  • $15.00 Shipping
For   PRIME B250M-J 1151 pin M.2 Game Motherboard 8100f
Quick View
  •  
  • $218.90 
  • $15.00 Shipping
For A7000 E4980I Motherboard PIG41F L-IG41S2 DDR3
Quick View
  •  
  • $108.90 
  • $5.00 Shipping
For     560 560S Motherboard G43T-DM1 18D1Y DDR3
Quick View
  •  
  • $83.60 
  • $15.00 Shipping
For   IPM17-DD 799929-001 V1.04 Version 1151 Motherboard
Quick View
  •  
  • $163.90 
  • $15.00 Shipping
For   STRIX Z270H   Desktop Motherboard 1151 Pin
Quick View
  •  
  • $284.90 
  • $15.00 Shipping
For   Z97-K R2.0 1150 Motherboard Z97 Supports I7 5775C
Quick View
  •  
  • $218.90 
  • $5.00 Shipping
For W26361-W1611-X-02 D2608-A11 M460 main motherboard
Quick View
  •  
  • $1,765.00 
  • $5.00 Shipping
For W26361-W2481-X-02 W510 main motherboard D3067-A11
Quick View
  •  
  • $574.00 
  • $5.00 Shipping
For IL40 main motherboard W26361-W52-X-02 D1527-A21
Quick View
  •  
  • $736.00 
  • $5.00 Shipping

Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP