Which printers are compatible with the Canon CLI-251 XL High Yield Ink Cartridge?

The cartridge is compatible with Canon PIXMA MG5420, MG5422, MG5520, MG5522, MG6320, MG6420, MG7120, MX722, MX922, iP7220, iP8720, and iX6823.

What is the page yield of the Canon CLI-251 XL Black Ink Cartridge?

The approximate page yield per cartridge is 660 pages.

Can the 251 BK XL cartridge be used in place of a 251 BK in a MG5420 printer ?

Yes, interchangeably. I get about double the printed pages with the XL tanks. Ken

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Canon CLI-251 XL High Yield Ink Cartridge - Black

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Black
Model #: 6448B001
Single Cartridge
Approx page yield per Cartridge: 660
Compatible with: Canon PIXMA MG6620, MX922 , MG5620 , MG5420 , MG7520 , iP7220 , MG7120 , iP8720 , iX6820 , MG6320 , MG6420 , MG5520 Series

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CLI-251XL Black Ink Tank for the MG6320 , IP7220 & MG5420, MX922, MG5520, MG6420, MG7120, iX6820, iX8720

Model
Brand	Canon
Model	CLI-251XL BK (6448B001)
Part Number	6448B001

Details
Cartridge Quantity	Single Pack
Cartridge Color	Black
Compatible Products	PIXMA MG5420, PIXMA MG5422, PIXMA MG5520, PIXMA MG5522, PIXMA MG6320, PIXMA MG6420, PIXMA MG7120, PIXMA MX722, PIXMA MX922, PIXMA iP7220, PIXMA iP8720, PIXMA iX6823
Ink Type	Dye-based

Features
Features	This CLI-251 Black Ink Tank delivers improved color, a wider color gamut and better color fastness. Print only with genuine Canon ink and photo paper to achieve optimum results through the ChromaLife100+ System which will deliver stunning results and longevity. Remember, a genuine Canon XL ink cartridge means high capacity, which means more ink for more prints!

Additional Information
First Listed on Newegg	June 11, 2026

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Canon CLI-251 XL High Yield Ink Cartridge - Black

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Item#: 9SIAE1AKJM1019

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Canon CLI-251 XL High Yield Ink Cartridge - Black

Learn more about the Canon CLI-251XL BK (6448B001)

Customer Reviews of the Canon CLI-251XL BK (6448B001)

Warranty & Returns

Warranty, Returns, And Additional Information

Warranty

Return Policies

Manufacturer Contact Info