Pros: - Worked right out of the box - Support up to 768GB of DDR4 ECC - Good for multiple GPUs setup - Works with H0 CPU stepping

Cons: - If only they have more built-in M.2 slots to take advantage of all the PCI lanes from 2 CPUs. - Single CPU setup would be able to utilize only half of the memory/PCIE slots. - EEB form factor so there could be some drilling works if you have a normal case.

Overall Review: I have own this board for a few months, running 24/7 and it has never let me down since day 1. I rarely write review but it seems there are some unfair reviews for this product so I decided to share mine. Currently I am running a 2x8173m, 384GB DDR4 ECC, 3xGPUs setup for machine learning and other stuff. Initially, I did not purchased this board but the Supermicro MBD-X11SPA-TF-O (single CPU) brand new from Newegg, thinking Supermicro boards would be compatible with most of CPUs stepping including ES/QS. I actually own a pair of xeon 8173m CPUs with H0 stepping (not ES). The Supermicro board could not manage to boot a single time even with known working components - all it did was giving me a strange beep code that did not match any of the beep code that Supermicro has. I had to return it and replaced with this Asus board based on my previous perfectly positive experience with their products. The result was perfect once again! The system booted up immediately with both CPUs and all 12x32GB DDR4 ECC recognized. Both CPUs and memory sticks were purchased used on other sites. The great thing about Asus board is that it shows boot codes that I can easily look up and make changes accordingly if needed, much easier than the high/low pitched long/short beeps of Supermicro. Both Windows Server and Linux were installed on this system and it has been running 24/7 without issue ever since. There are a few minor drawbacks though. Firstly, I owned a Corsair 540 Air and this board is slightly wider (but still fit in the case just fine) as well as it needs different set of holes to screw in. This is not a big deal - took me ~15 minutes to align the board and drill some holes on the case. You might not be able to have all the holes with this case since some would fall on the rubber part of the case. Second drawback is that it only has 1 built-in M.2 slot. If you build a multi-GPU system, which is likely the case for using a dual CPU system, you would have no other slot for more M.2 SSD and has to use SATA SSD for additional storage or dual boot. It is quite a waste for 96 PCIE lanes from 2 CPUs. Finally, you will need both CPUs to use all PCIE and RAM slots, but this is quite expected for dual CPU boards. For the negative reviews about this board not working with ES/QS CPUs, this is not really Asus fault. Online sellers always show which boards they tested to work with their CPUs. It has been years that similar boards made by Asus, excluding server boards, are consumer grade and they only support retail or sometime QS CPUs (such as their X99 2011-v3 series). You should have known which board is compatible with your CPUs before buying it or buy compatible CPUs if you like this board... To sum up, get this motherboard if you know it works with your components and if you do have 2 CPUs to fully utilize all features. This is a costly setup but I am very happy with Asus quality so far, especially when it comes to motherboards.