Could this support 128 GB of RAM or more?

Yes, but the Mother Board has six channel memory with 12 DIMM slots. So 8GB x 12 DIMM = 96GB and 16GB x 12 DIMM = 192GB. I'm using a Corsair Vengeance 12 DIMM 192GB Kit for 3200 MHz speed. Be sure to reference supported memory on ASUS website because these large capacity DIMM Sets must be perfectly timed and Matched by Corsair. Enjoy. It's a great board.

Hello, Thank you for contacting us in regards to your question. This board is not an E-ATX. It is considered a 14''x 14'' EEB/ATX Form Factor. Thank you and have a nice day! Newegg Support

Does this support enough RAM to run Chrome?

depends on how much ram you have, if you have less then 1tb of ram then no you cannot run chrome. And that can only run one tab For every tab it is a terribyte of ram.

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Main image of ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 2 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 3 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 4 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 5 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

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ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Used - Like New

LGA 3647 socket, engineered to overclock Intel Xeon W-3175X processors
Designed for extreme performance, dual 24-pin, quad 8-pin and dual 6-pin 12V power connectors that deliver industry-leading power efficiency
Quad strength graphic power featuring 4-Way PCIe 3.0 link supporting NVIDIA GeForce SLI, NVIDIA NVLink and AMD CrossFireX
Built for high performance networking: Onboard Aquantia AQC-107 10G LAN, Intel I219-LM Gigabit LAN, Intel Wireless AC-9260 Wi-Fi (802.11 ac) and ROG GameFirst technology
5-Way Optimization featuring Auto-Tuning and FanXpert 4 provides automatic overclocking profiles for maximum OC performance, plus 14 PWM fan headers to support dynamic system cooling

🔥Don't forget your OS, we have Windows 11 OEM, Download and USB versions available

Overview

Specs

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Model
Brand	ASUS
Model	DOMINUS EXTREME

Supported CPU
CPU Socket Type	LGA 3647
CPU Type	Supports to Xeon W-3175X

Chipsets
Chipset	Intel C621

Memory
Number of Memory Slots	12x288pin (DDR4)
Memory Standard	Support up to DDR4 4200(O.C.)
Maximum Memory Supported	192GB
Channel Supported	Six Channel
ECC Supported	Yes

Expansion Slots
PCI Express 4.0 x16	4 x PCIe 3.0 x16 (x16/x16/x16, x16/x8/x16/x8)

Storage Devices
Serial ATA (SATA)	8 x SATA 6Gb/s
M.2	Intel Xeon W-3175X Processor: 2 x ROG DIMM.2 Module support (CPU_DIMM.2), with M key, type 2242/2260/2280/22110 storage devices support (PCIE 3.0 x4 mode)* 2 x U.2 connector* * The PCIEX16_2 shares bandwidth with the DIMM.2_2_2, U.2_2, DIMM.2_1_1 and DIMM.2_1_2 slots. * The PCIEX16_3 shares bandwidth with the DIMM.2_2_1 and U.2_1 slots. * The PCIEX16_4 shares bandwidth with the DIMM.2_1_1 and DIMM.2_1_2 slots.

Onboard Audio
Audio Channels	ROG SupremeFX 8-Channel High Definition Audio CODEC S1220 - Supports : Jack-detection, Multi-streaming, Front Panel Jack-retasking - High quality120dBSNR stereo playback outputand113dBSNR recording input - SupremeFX Shielding Technology - Supports up to 32-Bit/192kHz playback *2 Audio Feature : - Optical S/PDIF out port(s) at back panel - Sonic Radar III - Sonic Studio III + Sonic Studio Link

Onboard LAN
LAN Chipset	AQUANTIA AQC107
Second LAN Chipset	Intel I219-LM
Max LAN Speed	10Gbps + 1Gbps
Wireless LAN	Intel Wireless-AC 9260 Wi-Fi 802.11 a/b/g/n/ac Supports dual band frequency 2.4/5 GHz Supports MU-MIMO Supports channel bandwidth: HT20/HT40/HT80/HT160. Up to 1.73Gbps transfer speed
Bluetooth	Bluetooth 5.0

Rear Panel Ports
Back I/O Ports	2 x USB 3.2 Gen 2 (black)Type-C, 2 x USB 3.2 Gen 2 (red)Type-A 1 x USB BIOS FlashBack Button(s) 8 x USB 3.2 Gen 1 (blue) 5 x LED-illuminated audio jacks 1 x Aquantia AQC-107 10G LAN port 1 x Optical S/PDIF out 1 x Clear CMOS button(s) 1 x ASUS Wi-Fi Module Anti-surge LAN (RJ45) port

Internal I/O Connectors
Onboard USB	2 x USB 3.1 Gen 1(up to 5Gbps) connector(s) support(s) additional 4 USB 3.1 Gen 1 port(s) 2 x USB 2.0 connector(s) support(s) additional 4 USB 2.0 port(s)
Other Connectors	2 x Aura Addressable Strip Header(s) 1 x VROC_HW_Key 2 x LED connectors (Back I/O cover, PCH, OLED) 2 x Chassis Fan connector(s) (2 x 4-pin) 1 x PCH_FAN (1 x 3-pin) 2 x HS_FAN (2 x 4-pin) 2 x W_PUMP+ connector (2 x 4-pin) 1 x WB_SENSOR (1 x 9-pin) 1 x Thunderbolt header(s) 2 x 6-pin EATX 12V Power connector 2 x 24-pin EATX Power connector(s) 4 x 8-pin EATX 12V Power connectors 1 x 6-pin EZ_PLUG Power connector(s) 13 x ProbeIt Measurement Points 1 x BIOS Switch button(s) 2 x U.2 connector 1 x PCIe x16 lane switch 2 x T_Sensor Connector 1 x USB 3.1 Gen 2 front panel connector 2 x DIMM.2 Slot supports 2 M.2 drives (2242-22110) 1 x PAUSE Switch 2 x RSVD Switch 8 x Radiator Fan Headers 1 x Reset button 1 x Q-Code 2 x Aura RGB Strip Headers 8 x SATA 6Gb/s connector(s) 1 x CPU Fan connector(s) (1 x 4-pin) 1 x CPU OPT Fan connector(s) (1 x 4-pin) 1 x Front panel audio connector(s) (AAFP) 1 x Slow Mode switch(es) 1 x Node Connector(s) 1 x LN2 Mode jumper(s) 1 x Safe Boot button 1 x ReTry button 1 x 14-1 pin TPM connector 1 x System panel connector 1 x W_IN header 1 x W_OUT header 1 x W_FLOW header 1 x Speaker connector 1 x Start button

Software Feature
BIOS Feature	2 x 128 Mb Flash ROM, UEFI AMI BIOS, PnP, SM BIOS 3.1, ACPI 6.1, Multi-language BIOS, ASUS EZ Flash 3, CrashFree BIOS 3, Secure Erase, User Profile, F11 EZ RAID Wizard, F6 Qfan Control, F3 My Favorites, Last Modified log, F12 PrintScreen, , F4 AURA ON/OFF and F9 Search

Physical Spec
Form Factor	EEB
Dimensions (W x L)	14.0" x 14.0"

Features
Features	Multi-GPU Support: Supports NVIDIA 4-Way SLI Technology Supports NVIDIA 3-Way SLI Technology Supports NVIDIA 2-Way SLI Technology Supports AMD 4-Way CrossFireX Technology Supports AMD 3-Way CrossFireX Technology Supports AMD 2-Way CrossFireX Technology USB BIOS FlashBack Clear CMOS button - PCIe x16 Lane Switch ProbeIt ROG DIMM.2 module with heatsink ROG Aluminum heatsink cover Extreme Engine Digi+ : - MicroFine Alloy Chokes - 10K Black Metallic Capacitors ROG Extreme OC kit : - Safe Boot button - Slow Mode - LN2 Mode ROG Patented Pre-mounted I/O Shield ROG Exclusive Software - RAMCache III - RAMDisk - CPU-Z - GameFirst V - Overwolf - USB BIOS FlashBack - BIOS FlashBack Button LiveDash OLED 1.77" - BUPDATER Fan Xpert4 - Fan Xpert 4 featuring Fan Auto Tuning function and multiple thermistors selection for optimized system cooling control AURA : - Aura Lighting Control - Aura RGB Strip Headers - Aura Lighting Effects Synchronization with compatible ASUS ROG devices - Aura Addressable Strip Header(s) ASUS Exclusive Features : - AI Suite 3 - ASUS CrashFree BIOS 3 - ASUS NODE: hardware control interface - ASUS EZ Flash 3 - ASUS C.P.R.(CPU Parameter Recall) - Clear CMOS Button ASUS Q-Design : - ASUS Q-Code - ASUS Q-Slot - ASUS Q-DIMM - ASUS Q-Connector

Packaging
Package Contents	Accessories: User's manual 1 x ROG logo plate sticker 4 x M.2 Screw Package 1 x CPU installation tool 1 x ASUS 2T2R dual band Wi-Fi moving antennas (Wi-Fi 802.11 a/b/g/n/ac compliant) 1 x Fan Extension Card II (6 x 4-pin Chassis Fan connectors, 3 x RGB headers, 3 x 2-pin Thermal sensor header) 1 x Fan Extension Card II power cable 1 x Fan Extension Card II NODE connector cable 1 x Fan Extension Card II screw package 1 x SLI HB BRIDGE (2-WAY-L) 1 x Q-Connector 1 x ROG Logo Sticker(s) 1 x Extension Cable for RGB strips (80cm) 1 x Extension cable for Addressable LED 3 x Thermistor cable(s) 1 x USB drive with utilities and drivers 1 x ROG coaster(s) 8 x ROG weave SATA 6G cable 2 x ROG DIMM.2 with heatsink 2 x M.2 Pad for ROG DIMM.2

Additional Information
First Listed on Newegg	June 15, 2026

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