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600 G4 SFF L05338-001, 601 L02433-001 8th Generation Main Board
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600 G4 SFF L05338-001, 601 L02433-001 8th Generation Main Board

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600 G3 SFF Main Board 911988-001/601 901198-001 7th Generation
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600 G3 SFF Main Board 911988-001/601 901198-001 7th Generation

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600 G4 SFF Main Board L05338-001/601 L02433-001 8th Generation
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600 G4 SFF Main Board L05338-001/601 L02433-001 8th Generation

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405 485G2MT MS-7938 V1.0 Integrated Main Board 754091-001 753929-001
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405 485G2MT MS-7938 V1.0 Integrated Main Board 754091-001 753929-001

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14-AB 15-AB Main Board 809407-001 814751-001 Version Number: DA0X22MB6D0
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14-AB 15-AB Main Board 809407-001 814751-001 Version Number: DA0X22MB6D0

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GIGABYTE GA-H81M-D2V LGA1150/ Intel H81/ DDR3/ SATA3&USB3.0/ A&GbE/ MicroATX Motherboard
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GIGABYTE
Used - Very Good GIGABYTE GA-H81M-D2V LGA1150/ Intel H81/ DDR3/ SATA3&USB3.0/ A&GbE/ MicroATX Motherboard
  • CPU Type: Intel Core i3 / i5 / i7 / Pentium / Celeron
  • PCI Express x16: 1 x PCI Express x16
  • PCI Express x1: 2 x PCI Express x1
  • SATA: 2 x SATA 6Gb/s connectors (SATA3 0~SATA3 1) supporting up to 2 SATA 6Gb/s devices 2 x SATA 3Gb/s connectors (SATA2 2~SATA2 3) supporting up to 2 SATA 3Gb/s devices
  • Model #: Newegg_Delete
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E41-80 N40-80 N50-80 main board LA-B091P LA-C292P main board
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E41-80 N40-80 N50-80 main board LA-B091P LA-C292P main board

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240 246 G4 14-AC TPN-I119 Main Board 817886-001 6050A2730001
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240 246 G4 14-AC TPN-I119 Main Board 817886-001 6050A2730001

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400 G5 DM Main Board L52073 L69383-001/601 L64296-201 DAF80BMB6D
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400 G5 DM Main Board L52073 L69383-001/601 L64296-201 DAF80BMB6D

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Server Motherboard For For ProLiant ML110 G5 445072-001 457883-001 Good
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15Z-Q M6-N Main Board 782279-501 Version Number: 6050A2626301-MB-A02
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15Z-Q M6-N Main Board 782279-501 Version Number: 6050A2626301-MB-A02

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15-BS 250 G6 TPN-C129 Main Board L27838-001 Version Number: LA-E802P
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15-BS 250 G6 TPN-C129 Main Board L27838-001 Version Number: LA-E802P

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BooK 8540P 8540W Main Board 595764-001 Version Number: LA-4951P
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BooK 8540P 8540W Main Board 595764-001 Version Number: LA-4951P

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450 440 G2 Main Board 784118-601 782623-601 Version Number: LA-B181P
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450 440 G2 Main Board 784118-601 782623-601 Version Number: LA-B181P

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Z10PA-U8/10G-2S server main board C612 main board X99 E5 2680V3 set
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Z10PA-U8/10G-2S server main board C612 main board X99 E5 2680V3 set

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TPN-I132 14-CM 14-CY Main Board L23396-001 Version Number 6050A2983601
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TPN-I132 14-CM 14-CY Main Board L23396-001 Version Number 6050A2983601

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400 G5 SFF 8th Generation Main Board L05339-001/601 L02436-001
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400 G5 SFF 8th Generation Main Board L05339-001/601 L02436-001

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440 430 G3 Main Board 830935-001 830936-601 Version Number: DA0X61MB6G0
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440 430 G3 Main Board 830935-001 830936-601 Version Number: DA0X61MB6G0

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DC5750 Main Board M2RS485-BTX AM2 Main Board 432861-001 409305-001
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DC5750 Main Board M2RS485-BTX AM2 Main Board 432861-001 409305-001

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TPC-W051-MT 795 21L Main Board 941802-601 17525-1 Main Board
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TPC-W051-MT 795 21L Main Board 941802-601 17525-1 Main Board

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Main Board B545 B345 QLA13 LA-8502P 8501P REV: 1.0 Independent
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Main Board B545 B345 QLA13 LA-8502P 8501P REV: 1.0 Independent

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7060 SFF XE3 8th Generation Small Chassis Main Board NC2VH GD52N
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7060 SFF XE3 8th Generation Small Chassis Main Board NC2VH GD52N

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TPN-Q214 13-AN Main Board L37347-601 Version Number: DA0G7DMB8D0 SRFFZ
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TPN-Q214 13-AN Main Board L37347-601 Version Number: DA0G7DMB8D0 SRFFZ

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MD70-HB0 Dual X99 Main Board C612 Dual 10G Gigabit, Remote Management Z10PE-D16WS
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MD70-HB0 Dual X99 Main Board C612 Dual 10G Gigabit, Remote Management Z10PE-D16WS

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800 G4 DM Main Board L19394-001 L19393 L19395 L05127-002 L04546
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800 G4 DM Main Board L19394-001 L19393 L19395 L05127-002 L04546

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3567 main board 3578 3576 main board 15341-1 17841-1 main board
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3567 main board 3578 3576 main board 15341-1 17841-1 main board

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Slim 290-p030cn TPC-W049-SF main board L16570-001/601 17578-1
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Slim 290-p030cn TPC-W049-SF main board L16570-001/601 17578-1

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800G6 DM Mini 35W Main Board L79218-002 L86387-001 601 10th Generation
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800G6 DM Mini 35W Main Board L79218-002 L86387-001 601 10th Generation

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E52-80 E42-80 V310-14ISK V310-15IKB V110-15ast14AST Main Board
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E52-80 E42-80 V310-14ISK V310-15IKB V110-15ast14AST Main Board

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15R-N5010 M501R-M5010 N5110 main board independent integration
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15R-N5010 M501R-M5010 N5110 main board independent integration

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K53SC A53S K53SD K53SV K53E K53S main board independent integration
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K53SC A53S K53SD K53SV K53E K53S main board independent integration

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A45V K45V A85V P45V K45VD P45VJ Main Board LA-8221P LA-8224P
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A45V K45V A85V P45V K45VD P45VJ Main Board LA-8221P LA-8224P

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L33910-001 14-cf Computer Main Board 6050A2992901 L41568 L24460
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L33910-001 14-cf Computer Main Board 6050A2992901 L41568 L24460

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280/288 Pro G5 290 G3 MT Main Board L77540-001/601 L69522-002
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280/288 Pro G5 290 G3 MT Main Board L77540-001/601 L69522-002

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7000 Main Board 7000-13/-15AST 330S-14/-15/320S IKBR Main Board
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7000 Main Board 7000-13/-15AST 330S-14/-15/320S IKBR Main Board

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TCP-Q24 24-B Main Board 923277-001 Version Number: DA0N83MB6G0
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TCP-Q24 24-B Main Board 923277-001 Version Number: DA0N83MB6G0

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Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

Anonymous
11/12/2025 7:31:12 AM
Great Epyc motherboard

“ I would recommend this MB for a small Epyc server build (nice ATX size). ”

Supermicro Server Motherboard MBD-H13SSL-NT, Socket SP5 AMD 4th Gen EPYC™ 9004/9005, Up to 3TB 3DS ECC RDIMM DDR5, ATX. Support of "EPYC 5th Gen 9005 Series"
Dgunnell
10/21/2025 7:12:25 AM
Nice server motherboard

“ I would recommend this motherboard for a home based or small business server ”

ASRock Rack Server Motherboard EC266D2I Mini-ITX 2x 1GLan Single Socket (LGA 1700) Intel Xeon E-2400 series
John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP
RICHARD B.
8/18/2025 5:25:53 AM
Doing GREAT so far (updated 1 wek in)

“ I would definitely recommend this board for your server build. ”

ASRock Rack Server Motherboard B650D4U3-2L2Q/BCM Micro-ATX AMD EPYC™ 4004/4005 and AMD Ryzen™ 9000/8000/7000 Series Dual SFP28 (25GbE)
Anonymous
7/16/2025 11:50:37 AM
Epyc 4005 worked after bios update

“ Plenty of pcie lanes for small businesses or home lab I would still recommend this board to start with, as you can always use the two other pcie lanes for expansions and leave the full 16x for a GPU or whatnot. ”

ASRock Rack B650D4U-2L2T/BCM Micro-ATX Server Motherboard Single Socket AMD EPYC™ 4005/4004 and AMD Ryzen™ 9000/8000/7000 Series Processors (LGA 1718) B650E PCIe 5.0 Dual 10G Lan
Ryland P.
6/13/2025 9:24:32 AM
SFF server board crammed with features

“ Tons of features peculiar to server boards but in a SFF ”

Supermicro MBD-X13SCL-IF-O Intel LGA-1700 Single Socket Mini-ITX Server Motherboard
Anonymous
4/15/2025 10:18:04 AM
Perfect for a server

“ Overall a great choice for a server platform using Ryzen AM5 CPUs rather than EPYC or Xeon while getting mostly the same management features. ”

ASRock Rack B650D4U-2L2T/BCM Micro-ATX Server Motherboard Single Socket AMD EPYC™ 4005/4004 and AMD Ryzen™ 9000/8000/7000 Series Processors (LGA 1718) B650E PCIe 5.0 Dual 10G Lan