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TPN-I132 14-CM 14-CY Main Board L23396-001 Version Number 6050A2983601
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11-K Main Board 809560-001 813676-001 Version Number: 14258-2
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800 G4 DM Main Board L19394-001 L19393 L19395 L05127-002 L04546
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Slim 290-p030cn TPC-W049-SF main board L16570-001/601 17578-1
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3567 main board 3578 3576 main board 15341-1 17841-1 main board
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MD70-HB0 Dual X99 Main Board C612 Dual 10G Gigabit, Remote Management Z10PE-D16WS
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MD70-HB0 Dual X99 Main Board C612 Dual 10G Gigabit, Remote Management Z10PE-D16WS

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L33910-001 14-cf Computer Main Board 6050A2992901 L41568 L24460
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L33910-001 14-cf Computer Main Board 6050A2992901 L41568 L24460

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Main Board B545 B345 QLA13 LA-8502P 8501P REV: 1.0 Independent
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800G6 DM Mini 35W Main Board L79218-002 L86387-001 601 10th Generation
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800G6 DM Mini 35W Main Board L79218-002 L86387-001 601 10th Generation

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A45V K45V A85V P45V K45VD P45VJ Main Board LA-8221P LA-8224P
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9020 7020 T1700 SFF Main Board XCR8D 2621G 0V62H TDG4V 3X0YG
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9020 7020 T1700 SFF Main Board XCR8D 2621G 0V62H TDG4V 3X0YG

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405 485G2MT MS-7938 V1.0 Integrated Main Board 754091-001 753929-001
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405 485G2MT MS-7938 V1.0 Integrated Main Board 754091-001 753929-001

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15-CR Main Board L20846-601 L22448-601 Version Number: 17881-1B
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15-CR Main Board L20846-601 L22448-601 Version Number: 17881-1B

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K53SC A53S K53SD K53SV K53E K53S main board independent integration
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G14 248 340 350 G1 Main Board 759268-501 Version Number: 6050A2645501
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G14 248 340 350 G1 Main Board 759268-501 Version Number: 6050A2645501

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TPN-C135 15-DA 15-DI Main Board L20374-001 Version LA-G07EP SR3W0
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TPN-C135 15-DA 15-DI Main Board L20374-001 Version LA-G07EP SR3W0

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TCP-Q24 24-B Main Board 923277-001 Version Number: DA0N83MB6G0
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TCP-Q24 24-B Main Board 923277-001 Version Number: DA0N83MB6G0

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3670 3671 MT Main Board R6JMP 1W26N H4VK7 V8F20 17529-1 19422
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3670 3671 MT Main Board R6JMP 1W26N H4VK7 V8F20 17529-1 19422

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400 G5 DM Main Board L52073 L69383-001/601 L64296-201 DAF80BMB6D
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400 G5 DM Main Board L52073 L69383-001/601 L64296-201 DAF80BMB6D

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TPC-W051-MT 795 21L Main Board 941802-601 17525-1 Main Board
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TPC-W051-MT 795 21L Main Board 941802-601 17525-1 Main Board

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15-BS 250 G6 TPN-C129 Main Board L27838-001 Version Number: LA-E802P
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15-BS 250 G6 TPN-C129 Main Board L27838-001 Version Number: LA-E802P

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X10DRL-i Dual Server Main Board Support E5-2678V3 V4 Processor
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X10DRL-i Dual Server Main Board Support E5-2678V3 V4 Processor

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14-CD TPN-W131 Main Board L18175-001 Version Number: 17879-1B SR3W0
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14-CD TPN-W131 Main Board L18175-001 Version Number: 17879-1B SR3W0

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TPN-C136 15-DB 15-DX Main Board L68771-601 Version Number: LA-G076P
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7000 Main Board 7000-13/-15AST 330S-14/-15/320S IKBR Main Board
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7000 Main Board 7000-13/-15AST 330S-14/-15/320S IKBR Main Board

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15R-N5010 M501R-M5010 N5110 main board independent integration
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15R-N5010 M501R-M5010 N5110 main board independent integration

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E6320 E6220 E6230 E6330 Main Board LA-7731P 7741P 6611P 6612P
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E6320 E6220 E6230 E6330 Main Board LA-7731P 7741P 6611P 6612P

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13-AG 13Z-AG TPN-W133 Main Board L19572-601 Version Number: 17885-2
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13-AG 13Z-AG TPN-W133 Main Board L19572-601 Version Number: 17885-2

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M2600d 5900d 310s Integrated J4005 5005 A6 A9 9425 E2 Main Board
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TG01 TE01 Genie 6 10th Generation 11th Generation Main Board L75365-001 M16092-001
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TG01 TE01 Genie 6 10th Generation 11th Generation Main Board L75365-001 M16092-001

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5000 Main Board 5000G 320-15 IKB ISK Main Board NM-244 NM-242 Main Board
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5000 Main Board 5000G 320-15 IKB ISK Main Board NM-244 NM-242 Main Board

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ROCKY-4786EV-RS-R41/R40 Ver: 4.1/4 Main Board Single Network Port
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E5-471 K4000 E5-474 P248 Main Board N15C1 ZQ0 LA-C611P Main Board
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6470B 8470W 8470P Main Board 686038-001 Version Number: 6050A2470001
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6470B 8470W 8470P Main Board 686038-001 Version Number: 6050A2470001

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800G6 DM Mini 65W Main Board L79217-002 M87921-001 601 600G6
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800G6 DM Mini 65W Main Board L79217-002 M87921-001 601 600G6

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Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP