Could this support 128 GB of RAM or more?

Yes, but the Mother Board has six channel memory with 12 DIMM slots. So 8GB x 12 DIMM = 96GB and 16GB x 12 DIMM = 192GB. I'm using a Corsair Vengeance 12 DIMM 192GB Kit for 3200 MHz speed. Be sure to reference supported memory on ASUS website because these large capacity DIMM Sets must be perfectly timed and Matched by Corsair. Enjoy. It's a great board.

Hello, Thank you for contacting us in regards to your question. This board is not an E-ATX. It is considered a 14''x 14'' EEB/ATX Form Factor. Thank you and have a nice day! Newegg Support

Does this support enough RAM to run Chrome?

depends on how much ram you have, if you have less then 1tb of ram then no you cannot run chrome. And that can only run one tab For every tab it is a terribyte of ram.

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Main image of ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 2 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 3 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 4 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Alt view image 5 of 5 - ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

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ASUS ROG Dominus Extreme Intel LGA 3647 for Xeon W-3175X (C621) 12 DIMM DDR4 DIMM.2 U.2 EEB Performance Motherboard with Aquantia 10G LAN, USB 3.1

Used - Very Good

Comes with I/O shield and WiFi antenna, no other accessories.

LGA 3647 socket, engineered to overclock Intel Xeon W-3175X processors
Designed for extreme performance, dual 24-pin, quad 8-pin and dual 6-pin 12V power connectors that deliver industry-leading power efficiency
Quad strength graphic power featuring 4-Way PCIe 3.0 link supporting NVIDIA GeForce SLI, NVIDIA NVLink and AMD CrossFireX
Built for high performance networking: Onboard Aquantia AQC-107 10G LAN, Intel I219-LM Gigabit LAN, Intel Wireless AC-9260 Wi-Fi (802.11 ac) and ROG GameFirst technology
5-Way Optimization featuring Auto-Tuning and FanXpert 4 provides automatic overclocking profiles for maximum OC performance, plus 14 PWM fan headers to support dynamic system cooling

🔥Don't forget your OS, we have Windows 11 OEM, Download and USB versions available

Overview

Specs

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Model
Brand	ASUS
Series	ROG
Model	DOMINUS EXTREME

Supported CPU
CPU Socket Type	LGA 3647
CPU Type	Intel Socket 3647 for Xeon W-3175X Processors Supports Intel Virtual RAID on CPU (VROC) * Refer to www.asus.com for CPU support list

Chipsets
Chipset	Intel C621

Memory
Number of Memory Slots	12x288pin (DDR4)
Memory Standard	DDR4 4200(O.C.)/ 4000(O.C.)/ 3800(O.C.)/ 3733(O.C.)/ 3600(O.C.)/ 3466(O.C.)/ 3400(O.C.)/ 3200(O.C.)/ 3000(O.C.)/ 2933(O.C.)/ 2800(O.C.)/ 2666/ 2400/ 2133 MHz ECC and non-ECC, Un-buffered Memory Supports Intel Extreme Memory Profile (XMP) * Hyper DIMM support is subject to the physical characteristics of individual CPUs. * Refer to www.asus.com for the Memory QVL (Qualified Vendors Lists).
Maximum Memory Supported	192GB
Channel Supported	Six Channel

Expansion Slots
PCI Express 3.0 x16	48-Lane CPU: Intel Xeon W-3175X Processor 4 x PCIe 3.0 x16 (x16/x16/x16, x16/x8/x16/x8) * * The PCIEX16_2 shares bandwidth with the DIMM.2_2_2, U.2_2, DIMM.2_1_1 and DIMM.2_1_2 slots. * The PCIEX16_3 shares bandwidth with the DIMM.2_2_1 and U.2_1 slots. * The PCIEX16_4 shares bandwidth with the DIMM.2_1_1 and DIMM.2_1_2 slots.

Storage Devices
Serial ATA (SATA)	Intel C621 Chipset: 6 x SATA 6Gb/s port(s) ASMedia SATA 6Gb/s controller: 2 x SATA 6Gb/s port(s)
M.2	Intel Xeon W-3175X Processor: 2 x ROG DIMM.2 Module support (CPU_DIMM.2), with M key, type 2242/2260/2280/22110 storage devices support (PCIE 3.0 x4 mode)* 2 x U.2 connector* * The PCIEX16_2 shares bandwidth with the DIMM.2_2_2, U.2_2, DIMM.2_1_1 and DIMM.2_1_2 slots. * The PCIEX16_3 shares bandwidth with the DIMM.2_2_1 and U.2_1 slots. * The PCIEX16_4 shares bandwidth with the DIMM.2_1_1 and DIMM.2_1_2 slots.
Intel Optane Ready	Yes

Onboard Audio
Audio Chipset	ROG SupremeFX High Definition Audio CODEC S1220
Audio Channels	8 Channels * Due to limitations in HDA bandwidth, 32-Bit / 192 kHz is not supported for 8-Channel audio.

Onboard LAN
LAN Chipset	AQUANTIA AQC107
Second LAN Chipset	Intel I219-LM
Max LAN Speed	10Gbps + 1Gbps
Wireless LAN	Intel Wireless-AC 9260 Wi-Fi 802.11 a/b/g/n/ac Supports dual band frequency 2.4/5 GHz Supports MU-MIMO Supports channel bandwidth: HT20/HT40/HT80/HT160. Up to 1.73Gbps transfer speed
Bluetooth	Bluetooth 5.0

Rear Panel Ports
RJ45	1 x Aquantia AQC-107 10G LAN port Anti-surge LAN (RJ45) port
USB 3.1	2 x USB 3.1 Gen 2 Type-C 2 x USB 3.1 Gen 2 Type-A 8 x USB 3.1 Gen 1 (blue)
S/PDIF Out	1 x Optical
Audio Ports	5 x LED-illuminated audio jacks
Antenna Connectors	1 x ASUS Wi-Fi Module

Internal I/O Connectors
Onboard USB	1 x USB 3.1 Gen 2 front panel connector 2 x USB 3.1 Gen 1 (up to 5Gbps) connector(s) support(s) additional 4 USB 3.1 Gen 1 port(s) 2 x USB 2.0 connector(s) support(s) additional 4 USB 2.0 port(s)
Other Connectors	2 x Aura Addressable Strip Header(s) 2 x Aura RGB Strip Headers 1 x VROC_HW_Key 1 x CPU Fan connector(s) (1 x 4-pin) 1 x CPU OPT Fan connector(s) (1 x 4-pin) 2 x LED connectors (Back I/O cover, PCH, OLED) 2 x Chassis Fan connector(s) (2 x 4-pin) 1 x PCH_FAN (1 x 3-pin) 2 x HS_FAN (2 x 4-pin) 2 x W_PUMP+ connector (2 x 4-pin) 1 x WB_SENSOR (1 x 9-pin) 1 x Thunderbolt header(s) 1 x Front panel audio connector(s) (AAFP) 1 x Slow Mode switch(es) 13 x ProbeIt Measurement Points 1 x BIOS Switch button(s) 1 x Node Connector(s) 1 x LN2 Mode jumper(s) 1 x Safe Boot button 1 x ReTry button 1 x 14-1-pin TPM connector 1 x System panel connector 1 x PCIe x16 lane switch 2 x T_Sensor Connector 1 x W_IN header 1 x W_OUT header 1 x W_FLOW header 1 x Speaker connector 1 x PAUSE Switch 2 x RSVD Switch 8 x Radiator Fan Headers 1 x Start button 1 x Reset button 1 x Q-Code

Physical Spec
Form Factor	EEB
LED Lighting	RGB
Dimensions (W x L)	14.0" x 14.0"
Power Pin	2 x 6-pin EATX 12V Power connector 2 x 24-pin EATX Power connector(s) 4 x 8-pin EATX 12V Power connectors 1 x 6-pin EZ_PLUG Power connector(s)

Features
Features	Multi-GPU Support: Supports NVIDIA 4-Way SLI Technology Supports NVIDIA 3-Way SLI Technology Supports NVIDIA 2-Way SLI Technology Supports AMD 4-Way CrossFireX Technology Supports AMD 3-Way CrossFireX Technology Supports AMD 2-Way CrossFireX Technology ROG Exclusive Features: Clear CMOS button Extreme Engine Digi+: - MicroFine Alloy Chokes - 10K Black Metallic Capacitors ROG Extreme OC kit: - ReTry button - Safe Boot button - Start button - Reset button - Slow Mode - LN2 Mode - PCIe x16 Lane Switch ProbeIt USB BIOS Flashback ROG Patented Pre-mounted I/O Shield ROG Exclusive Software - RAMCache III - RAMDisk - CPU-Z - GameFirst V - Sonic Studio III + Sonic Studio Link - Sonic Radar III - Overwolf ROG DIMM.2 module with heatsink ROG Aluminum heatsink cover Special Features: Fan Xpert4 - Fan Xpert 4 featuring Fan Auto Tuning function and multiple thermistors selection for optimized system cooling control LiveDash OLED 1.77" AURA: - Aura Lighting Control - Aura RGB Strip Headers - Aura Lighting Effects Synchronization with compatible ASUS ROG devices - Aura Addressable Strip Header(s) ASUS Exclusive Features: - USB BIOS Flashback - AI Suite 3 - ASUS CrashFree BIOS 3 - ASUS NODE: hardware control interface - ASUS EZ Flash 3 - ASUS C.P.R. (CPU Parameter Recall) - BUPDATER - BIOS Flashback Button - Clear CMOS Button ASUS Q-Design: - ASUS Q-Code - ASUS Q-Slot - ASUS Q-DIMM - ASUS Q-Connector BIOS: 2 x 128MB Flash ROM, UEFI AMI BIOS, PnP, SM BIOS 3.1, ACPI 6.1, Multi-language BIOS, ASUS EZ Flash 3, CrashFree BIOS 3, Secure Erase, User Profile, F11 EZ RAID Wizard, F6 Qfan Control, F3 My Favorites, Last Modified log, F12 PrintScreen, F4 AURA ON/OFF and F9 Search Manageability: WOL, WOR, PXE Support Disc: Drivers EZ Update Anti-virus software (OEM version) ASUS Utilities Operating System: Windows 10 64-bit

Packaging
Package Contents	Accessories: User's manual 1 x ROG logo plate sticker 4 x M.2 Screw Package 1 x CPU installation tool 1 x ASUS 2T2R dual band Wi-Fi moving antennas (Wi-Fi 802.11 a/b/g/n/ac compliant) 1 x Fan Extension Card II (6 x 4-pin Chassis Fan connectors, 3 x RGB headers, 3 x 2-pin Thermal sensor header) 1 x Fan Extension Card II power cable 1 x Fan Extension Card II NODE connector cable 1 x Fan Extension Card II screw package 1 x SLI HB BRIDGE (2-WAY-L) 1 x Q-Connector 1 x ROG Logo Sticker(s) 1 x Extension Cable for RGB strips (80cm) 1 x Extension cable for Addressable LED 3 x Thermistor cable(s) 1 x USB drive with utilities and drivers 1 x ROG coaster(s) 8 x ROG weave SATA 6G cable 2 x ROG DIMM.2 with heatsink 2 x M.2 Pad for ROG DIMM.2

Additional Information
First Listed on Newegg	April 01, 2026

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