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iMicro 10 Pack MO-WVEO01 2.4GHz Wireless Vertical Ergonomic Optical Mouse,
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  • $119.90 
  • Free Shipping
MATIAS WIRELESS USB-C MOUSE BLACK
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MATIAS WIRELESS USB-C MOUSE BLACK
  • Brand: Matias
  • Type: see description
  • Model #:
VERBATIM AMERICAS LLC 98622 WIRELESS DESKTOP MOUSE BLACK
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VERBATIM AMERICAS LLC 98622 WIRELESS DESKTOP MOUSE BLACK
  • Brand: VERBATIM AMERICAS LLC
  • Type: RF Wireless
  • Model #: 98622
Innovera Mouse,2.4g,Laser,Wrls,Bk 62500
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Innovera Mouse,2.4g,Laser,Wrls,Bk 62500
  • Brand: Innovera
  • Name: IVR62500
  • Color: Black
  • Buttons: 3
  • Model #: 62500
Innovera Mouse,Wrls,Mid-Size,Bk 61500
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EXPERT MOUSE OPTICAL
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EXPERT MOUSE OPTICAL
  • Parts: 5 Year
  • Model #: 64325
Innovera Mouse,Optl,Wrls,Min,Bk 62210
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Kensington SlimBlade K72327US Red Scroll Ball USB Wired Laser Mouse
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Kensington SlimBlade K72327US Red Scroll Ball USB Wired Laser Mouse
  • Operating System Supported: Mac OS, Vista, Windows 10, Windows 7, Windows 8, XP
  • Model #: K72327US
Urban Factory Mouse WMB01UF
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R-Go HE Mouse Ergonomic Wired Medium Left Hand RGOHELELA
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  • $67.11 
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R-Go HE Basic Vertical Mouse, Right Handed RGOHEBAMRWL
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R-Go HE Basic Vertical Mouse, Right Handed RGOHEBAMRWL
  • Brand: R-Go
  • Type: see description
  • Model #:
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  • $57.65 
  • Free Shipping
iMicro MO-WVEO01 2.4GHz Wireless Vertical Ergonomic Optical Mouse
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  • $14.99 
  • $7.85 Shipping
HP Wireless Rechargeable 950MK Mouse and Keyboard
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HP
HP Wireless Rechargeable 950MK Mouse and Keyboard
  • Part Number: 3M165AA#ABA
  • Features: HP Wireless Rechargeable 950MK Mouse and Keyboard
  • Model #: 3M165AA#ABA
Perixx PERIMICE-719 Wireless 2.4GHz Ergonomic Small Vertical Optical Mouse - Portable Small Design - 3 Adjustable DPI(800/1200/1600)  - Black - Nano USB receiver Included
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Perixx PERIMICE-719 Wireless 2.4GHz Ergonomic Small Vertical Optical Mouse - Portable Small Design - 3 Adjustable DPI(800/1200/1600) - Black - Nano USB receiver Included
  • Hand Orientation: Right Hand
  • Resolution (DPI): 800/1200/1600
  • Power Supply: 1 x AA Battery
  • Windows Vista: Works with Windows Vista
  • Model #: 11522
HP Active Pen with App Launch
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HP
HP Active Pen with App Launch
  • Model #: 556-936436000293306
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  • $16.99 
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R-Go HE Break ergonomic mouse RGOHBRSWLBL
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R-Go HE Break ergonomic mouse RGOHBRSWLBL
  • Brand: R-Go
  • Type: see description
  • Model #:
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  • $83.45 
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Kensington Orbit K72337 Black Wired Optical Trackball
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Kensington Orbit K72337 Black Wired Optical Trackball
  • Hand Orientation: Both Hands
  • Operating System Supported: Mac OS X 10.11 Mac OS 10.9 Mac OS 10.8 Windows 10 Windows 8.1 Windows 8 Windows 7 Mac OS X 10.10 Chrome OS 44 and above
  • Package Contents: 55691L
  • Model #: K72337US
Evoluent Vertical Mouse D Right Wired Medium
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Evoluent Vertical Mouse D Right Wired Medium
  • Brand: Evoluent
  • Type: Wired
  • Model #: VMDM
ERGOGUYS WP-012-BK-E WOW PEN JOY II WIRED VERTICAL
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ERGOGUYS WP-012-BK-E WOW PEN JOY II WIRED VERTICAL
  • Hand Orientation: Right Hand
  • Resolution (DPI): 800 dpi
  • Package Contents: JOY Optical Mouse User Guide
  • Parts: 1 year limited
  • Model #: WP-012-BK-E
Mousebean Ergonomic Hand Rest Violet/Cerise HM68945
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  • $21.84 
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R-GO TWISTER ERGONOMIC MOUSE, PORTABLE, AMBIDEXTROUS
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R-GO TWISTER ERGONOMIC MOUSE, PORTABLE, AMBIDEXTROUS
  • Brand: R-Go
  • Type: see description
  • Model #:
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  • $100.22 
Adesso iMouse E90 Wireless Left-Handed Vertical Ergonomic Mouse
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Adesso iMouse E90 Wireless Left-Handed Vertical Ergonomic Mouse
  • Hand Orientation: Left Hand
  • Resolution (DPI): 1600 dpi
  • Power Supply: 2 x AAA Batteries
  • Operating System Supported: Windows 2000 / XP / Vista / 7 / 8 / 10
  • Model #: IMOUSEE90
Kantek Sit-Stand Footrest FR915
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  • $24.99 
Kensington  K72352US Black RF Wireless Orbit Mobile Trackball
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Kensington K72352US Black RF Wireless Orbit Mobile Trackball
  • Hand Orientation: Both Hands
  • Operating System Supported: PC and Mac compatible, Compatible with Windows7, Windows XP, Windows Vista and Mac OS X
  • Package Contents: 21902Q
  • Parts: 5 Year
  • Model #: K72352US
HANDSHOE  MOUSE - RIGHT HAND - WIRELESS
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HANDSHOE MOUSE - RIGHT HAND - WIRELESS
  • Resolution (DPI): 1500 dpi
  • Parts: 3 Year
  • Model #: M2UB-LC
BORND E220 3 Buttons 1 x Wheel USB 2.0 RF Wireless Optical Mouse - Wide-Rainbow
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BORND E220 3 Buttons 1 x Wheel USB 2.0 RF Wireless Optical Mouse - Wide-Rainbow
  • Resolution (DPI): 2000 dpi
  • Power Supply: 2x AA Alkaline Batteries (Included)
  • Operating System Supported: Windows 98/ 2000/ XP/ ME/ Vista/ 7 Mac OS
  • Model #: E220 Wide-Rainbow
BORND E220 3 Buttons 1 x Wheel USB 2.0 RF Wireless Optical Mouse - Slim-Rainbow
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BORND E220 3 Buttons 1 x Wheel USB 2.0 RF Wireless Optical Mouse - Slim-Rainbow
  • Resolution (DPI): 2000 dpi
  • Power Supply: 2x AA Alkaline Batteries (Included)
  • Operating System Supported: Windows 98/ 2000/ XP/ ME/ Vista/ 7 Mac OS
  • Model #: E220 Slim-Rainbow
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  • $38.09 
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HANDSHOE  MOUSE - RIGHT HAND - WIRED SM
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HANDSHOE MOUSE - RIGHT HAND - WIRED SM
  • Resolution (DPI): 1500 dpi
  • Model #: S2WB-LC
SLIMBLADE TRACKBALL SLIMBLADE TRACKBALL
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  • $124.37 - $131.62

Computer mice often are the unsung heroes of the home and office computing world. While your PC probably shipped with a standard mouse, if you haven't upgraded it, it is unlikely that you're getting the most from your time online or gaming. Modern Bluetooth mice can offer a seamless, virtually lag-free experience, while models with multiple buttons make it easier to keep pace with some of the best gamers in the world while enhancing your word processing and graphic design work. Shape and size determine how the mouse feels in your hand, with some people preferring lightweight models and others preferring something with extra heft. Button layout and configuration can greatly influence your mouse experience.

Laser Mice Offer Precision Movement

Computer mice use laser or optical sensors to track movement. Laser models track up to 2,000 dots per inch (dpi) while optical mice only track approximately 600. Most home users don't need the precision of a laser, and optical versions are less expensive. Graphic designers, videographers and serious gamers benefit from laser tracking because the movements on screen more precisely mirror the movement of the mouse.

Enjoy Greater Flexibility With Configurable Buttons

Most computer mice include left and right buttons, as well as a tracker wheel in the middle. Advanced versions can include two or four side buttons, and allow the user to configure these buttons to their own settings. A simple use may be to perform the function of the back button on your browser. Gamers might map a series of commands to one of these buttons, allowing them to pull off a complex move in one press.

Improve Mobility With Wireless Mice

Wired mice connect to a PC using USB or the PS/2 port. You will use the PS/2 port to connect other input devices such as keyboards so consider your configuration and whether you have a spare port available. If not, opt for a USB connection. PCs typically come with an array of ports so that you can connect mice and other USB gadgets. You can buy additional hubs that expand a single port to give four or more connections and allow the addition of all your computer accessories. Even wireless mice, which eliminate wire snags and make it easier to move your input device around, still require a USB port to connect the wireless receiver. They also take batteries or include a charging dock or wire.

Travel Mice Are Useful for Small Hands

Most portable and Bluetooth mice are smaller than their full-bodied counterparts. This is so that they will more easily fit into the pockets of a laptop bag and take up less space. However, they also offer benefits to users with smaller hands. It is important that you can comfortably fit your hand around a mouse, ensuring that your fingers rest easily over the buttons, and the diminutive form of travel mice makes this possible, even for children's hands.

Bestselling Mouse Reviews:

Andrew S.
1/5/2026 5:42:10 PM
The better ergo mouse

“ Having used a wired "gaming" vertical mouse and a cheaper wireless rechargeable one, this is really where I should have started. ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite
Anonymous
12/25/2025 9:35:25 AM
Mouse fits so comfortably!

“ I have had this mouse for years and it finally wore out. ”

Logitech - M500s Advanced Wired Optical Mouse with Hyper-fast Scrolling & Tilt - Wired - Black 910-007476
Steven K.
11/21/2025 9:17:37 AM
Great Mouse

“ Overall I like this mouse better than the traditional flat mouse. ”

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black
Don M.
10/13/2025 2:14:10 PM
Comfortable, reliable, long-lasting solution for hand and wrist pain

“ I've been using the MX Vertical Mouse for 5 years now, and only had to replace the mouse once in that time (spilled drink, not a product issue). ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite
Jaime G.
10/10/2025 3:17:53 PM
A LIFE SAVER For Carpal Tunnel Syndrome

“ I love this mouse so much I bought a couple of spares in case it gets discontinued. ”

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black