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EVOLUENT VM4 VERTICAL MOUSE LEFT HANDED - THE ERGONOMIC PATENTED SHAPE SUPPORTS
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  • $99.00 
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Evoluent Evoluent Right-Handed VerticalMouse 4 Wireless Mouse
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  • $120.00 
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Evoluent VM4L VerticalMouse 4 Left Hand Ergonomic Mouse with Wired USB Connection (Regular Size)
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  • $99.00 
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DXT Ergonomic Vertical Mouse for left and right hand PD7DXT 2
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  • $85.00 
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DXT Ergonomic Vertical Mouse for left and right hand PD7DXT 2
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  • $85.00 
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Evoluent Mouse VM4RW Vertical Mouse 4 Right Wireless Buttons
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  • $120.00 
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Evoluent VM4L Mouse VerticalMouse 4 Left USB 6 Button Brown Box
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  • $99.00 
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Evoluent Mouse VM4RM Vertical Mouse 4 Right Bluetooth
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  • $120.00 
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Evoluent VM4R Silver/Black 1 x Wheel USB Wired Laser Vertical Mouse
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  • $99.00 
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Evoluent VM4R VerticalMouse 4 Right Hand Ergonomic Mouse with Wired USB Conne...
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  • $99.00 
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Evoluent VM4R VerticalMouse 4 Ergonomic USB Mouse Med to Large Right Hand
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  • $99.00 
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Evoluent VM4R Mouse VerticalMouse 4 Right USB 6 Button Brown Box
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  • $99.00 
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Evoluent VM4S Vertical Mouse 4 Right Hand USB Wired (Small Size)
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  • $99.00 
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Evoluent VM4S Vertical Mouse 4 Right Hand USB Wired (Small Size)
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  • $99.00 
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Evoluent VM4 Vertical Mouse Right Handed - The Patented Shape Supports Your Hand
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  • $99.00 
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Adesso IMOUSEW4 IP65 Waterproof Antimicrobial Black USB Scroll Mouse
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  • $47.42 
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Evoluent VM4 Ergonomic Mouse Left
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  • $99.00 
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Kensington K72369US Pro Fit Full-Size Wired USB Optical Mouse w/ 2400 DPI (Black)
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  • $29.02 
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Prestige International Vm4Rw Evoluent Vertical Mouse 4 Wireless Right Handed-...
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  • $120.00 
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Innovera IVR62500 Black 6 Buttons 1 x Wheel USB 2.0 2.4 GHz Wireless Laser Hyper-Fast Scrolling Mouse
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Innovera IVR62500 Black 6 Buttons 1 x Wheel USB 2.0 2.4 GHz Wireless Laser Hyper-Fast Scrolling Mouse
  • Hand Orientation: Right Hand
  • Power Supply: 2 x AAA Batteries
  • Distance: Up to 26 ft.
  • Model #: IVR62500
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  • $25.23 
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Genuine Lenovo Blue Illuminating Wired USB 3-Button Black Optical Scroll Mouse MO09BO 41U3019 41U3018
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Refurbished Genuine Lenovo Blue Illuminating Wired USB 3-Button Black Optical Scroll Mouse MO09BO 41U3019 41U3018
  • Hand Orientation: Both Hands
  • Resolution (DPI): 800 dpi
  • System Requirement: Open USB Port
  • Version: Standard
  • Model #: 732341640804
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  • $30.00 
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Kensington GU1149B Kensington Pro Fit Full-Size Mouse USB (K72369US)
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Kensington GU1149B Kensington Pro Fit Full-Size Mouse USB (K72369US)
  • Hand Orientation: Right Hand
  • Resolution (DPI): 2400 dpi
  • Parts: 2 years limited
  • Labor: 2 years limited
  • Model #: GU1149B
Evoluent Vertical Mouse 4, Right Handed Model, Standard
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Cherry MW 9100 Rechargeable Wireless Mouse - Wireless - Bluetooth/Radio Frequency - 2.40 GHz - Yes - Black - USB - 2400 dpi - Scroll Wheel - 6 Button(s) - Symmetrical
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Cherry MW 9100 Rechargeable Wireless Mouse - Wireless - Bluetooth/Radio Frequency - 2.40 GHz - Yes - Black - USB - 2400 dpi - Scroll Wheel - 6 Button(s) - Symmetrical
  • Resolution (DPI): 2400 dpi
  • Operating System Supported: Windows 11 / Windows 7 / Windows 8 / Windows 10
  • System Requirement: USB port
  • Package Contents: MW 9100 Rechargeable Wireless Mouse USB Wireless Receive Transport Pouch USB Charging Cable Operating Instructions
  • Model #: JW-9100US-2
Evoluent Vertical Mouse 4, Right Handed Model, Small Size,
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Evoluent VerticalMouse 4 "Regular Size" Right Hand (model # VM4R) - USB Wired
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Evoluent VerticalMouse 4 Right Wireless VM4RW Plus Jestik Microfiber Cloth - Value Bundle
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  • $120.00 
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Evoluent VM4R VerticalMouse 4 Right Handed - The Patented Shape Supports Your Hand
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Computer mice often are the unsung heroes of the home and office computing world. While your PC probably shipped with a standard mouse, if you haven't upgraded it, it is unlikely that you're getting the most from your time online or gaming. Modern Bluetooth mice can offer a seamless, virtually lag-free experience, while models with multiple buttons make it easier to keep pace with some of the best gamers in the world while enhancing your word processing and graphic design work. Shape and size determine how the mouse feels in your hand, with some people preferring lightweight models and others preferring something with extra heft. Button layout and configuration can greatly influence your mouse experience.

Laser Mice Offer Precision Movement

Computer mice use laser or optical sensors to track movement. Laser models track up to 2,000 dots per inch (dpi) while optical mice only track approximately 600. Most home users don't need the precision of a laser, and optical versions are less expensive. Graphic designers, videographers and serious gamers benefit from laser tracking because the movements on screen more precisely mirror the movement of the mouse.

Enjoy Greater Flexibility With Configurable Buttons

Most computer mice include left and right buttons, as well as a tracker wheel in the middle. Advanced versions can include two or four side buttons, and allow the user to configure these buttons to their own settings. A simple use may be to perform the function of the back button on your browser. Gamers might map a series of commands to one of these buttons, allowing them to pull off a complex move in one press.

Improve Mobility With Wireless Mice

Wired mice connect to a PC using USB or the PS/2 port. You will use the PS/2 port to connect other input devices such as keyboards so consider your configuration and whether you have a spare port available. If not, opt for a USB connection. PCs typically come with an array of ports so that you can connect mice and other USB gadgets. You can buy additional hubs that expand a single port to give four or more connections and allow the addition of all your computer accessories. Even wireless mice, which eliminate wire snags and make it easier to move your input device around, still require a USB port to connect the wireless receiver. They also take batteries or include a charging dock or wire.

Travel Mice Are Useful for Small Hands

Most portable and Bluetooth mice are smaller than their full-bodied counterparts. This is so that they will more easily fit into the pockets of a laptop bag and take up less space. However, they also offer benefits to users with smaller hands. It is important that you can comfortably fit your hand around a mouse, ensuring that your fingers rest easily over the buttons, and the diminutive form of travel mice makes this possible, even for children's hands.

Bestselling Mouse Reviews:

Andrew S.
1/5/2026 5:42:10 PM
The better ergo mouse

“ Having used a wired "gaming" vertical mouse and a cheaper wireless rechargeable one, this is really where I should have started. ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite
Anonymous
12/25/2025 9:35:25 AM
Mouse fits so comfortably!

“ I have had this mouse for years and it finally wore out. ”

Logitech - M500s Advanced Wired Optical Mouse with Hyper-fast Scrolling & Tilt - Wired - Black 910-007476
Steven K.
11/21/2025 9:17:37 AM
Great Mouse

“ Overall I like this mouse better than the traditional flat mouse. ”

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black
Don M.
10/13/2025 2:14:10 PM
Comfortable, reliable, long-lasting solution for hand and wrist pain

“ I've been using the MX Vertical Mouse for 5 years now, and only had to replace the mouse once in that time (spilled drink, not a product issue). ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite
Jaime G.
10/10/2025 3:17:53 PM
A LIFE SAVER For Carpal Tunnel Syndrome

“ I love this mouse so much I bought a couple of spares in case it gets discontinued. ”

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black