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For   T350 G6C/R350 G6C Server S5000VSA Motherboard 11009720
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  • $625.90 
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For   Z820 Workstation Motherboard 618266-002 708464-001 708610-001
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  • $625.90 
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For   S5520SC Dual X58 Medical Workstation Main Board DAS50MB18C0
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  • $625.90 
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For  S7056GM3NR-HT-B-DWG I620-G15 Server Motherboard
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  • $625.90 
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For X7DB3 Server Motherboard 8-port SAS Supports 54  S
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  • $625.90 
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For   P9D-C/4L 1150 Pin Server Industrial  Motherboard
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  • $625.90 
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For   PowerEdge C6220 Server Motherboard 0083N0 2011 Pin
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  • $625.90 
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For X7DAL-E+dual 771-pin Device Motherboard With Sound Card
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  • $625.90 
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For  micro X8DAH+- F-QC001 Dual Server 2.01 Main Board
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  • $625.90 
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For W26361-W2481-X-02 W510 D3067-A11 GS1 Device Motherboard
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  • $625.90 
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SUPERMICRO MBD-X12SPI-TF-O ATX Server Motherboard LGA 4189 Intel C621A
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SUPERMICRO MBD-X12SPI-TF-O ATX Server Motherboard LGA 4189 Intel C621A

OUT OF STOCK

  • Brand: SUPERMICRO
  • CPU Socket Type: LGA 4189
  • CPU Type: Supports 3rd Gen Intel Xeon Scalable processors
  • North Bridge: Intel C621A
  • Model #: MBD-X12SPI-TF-O
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  • $639.00 
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For FB2LF-15 PWB R0076100 main motherboard
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  • $633.00 
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AsRock Rack W680D4U-2L2T/G5 Micro-ATX Server Motherboard Single Socket 12th & 13th Gen Intel® Core™ series processors (LGA 1700) W680 Dual 10G Lan PCIe 5.0
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ASRock Rack
AsRock Rack W680D4U-2L2T/G5 Micro-ATX Server Motherboard Single Socket 12th & 13th Gen Intel® Core™ series processors (LGA 1700) W680 Dual 10G Lan PCIe 5.0
  • Brand: AsRock Rack
  • CPU Socket Type: LGA 1700
  • CPU Type: Supports Intel Core 14th Gen, 13th & 12th Gen Intel Core series processors
  • Number of Processor Support: 1
  • Model #: W680D4U-2L2T/G5
For  micro X8DTH-6/6F Dual Channel Server Motherboard 1366 Pin X58 7 PCI-E
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  • $625.90 
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AsRock Rack SPC621D8U-2T Micro ATX Server Motherboard LGA 4189 Intel C621A
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ASRock Rack
AsRock Rack SPC621D8U-2T Micro ATX Server Motherboard LGA 4189 Intel C621A

OUT OF STOCK

  • Brand: AsRock Rack
  • CPU Socket Type: LGA 4189
  • CPU Type: Supports 3rd Gen Intel Xeon Scalable processors
  • Number of Processor Support: 1
  • Model #: SPC621D8U-2T
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  • $629.00 
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Supermicro H13SRA-F motherboard. AMD Ryzen™ Threadripper™ PRO 7000 WX-Series and Ryzen™ Threadripper™ 7000 Series Processors, Single socket sTR5, LGA-4844, Up to 350W TDP, Overclocking supported
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Supermicro
Supermicro H13SRA-F motherboard. AMD Ryzen™ Threadripper™ PRO 7000 WX-Series and Ryzen™ Threadripper™ 7000 Series Processors, Single socket sTR5, LGA-4844, Up to 350W TDP, Overclocking supported

OUT OF STOCK

  • Part Number: MBD-H13SRA-F-O
  • CPU Type: AMD Ryzen Threadripper PRO 7000 Series
  • Number of Processor Support: 1
  • Memory Standard: DDR5 4800
  • Model #: MBD-H13SRA-F-O
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  • $629.00 
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X99 Motherboard Set Dual CPU with E5 2680 V4 64GB DDR4 Ram 2400mhz Support USB3.0 SATA3 M.2 X99 Sever Combo
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  • $624.32 
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GIGABYTE MZ32-AR1 Motherboard - AMD EPYC™ 7003 - E-ATX UP RoT
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  • $619.00 
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GIGABYTE MW53-HP0 Intel® Xeon® W Workstation Motherboard Board, Single processor, LGA 4677, Intel® W790 Chipset.
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GIGABYTE
GIGABYTE MW53-HP0 Intel® Xeon® W Workstation Motherboard Board, Single processor, LGA 4677, Intel® W790 Chipset.
  • Brand: GIGABYTE
  • CPU Socket Type: LGA 4677
  • CPU Type: Intel Xeon W-3500* / W-2500 / W-3400* / W-2400 Processors
  • Number of Processor Support: 1
  • Model #: MW53-HP0
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  • $614.99 
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Intel DBS2600CW2R Xeon E5-2600 V3 LGA2011-V3 DDR4 SDRAM SSI EEB Motherboard
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  • $599.00 
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X99 AD4 Motherboard Combo with E5 2666 V3  DDR4 2x16GB RECC Set Kit Support M.2 PCI-E NVME NGFF ATX Server
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  • $611.66 
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X99 AD4 Motherboard Combo with E5 2666 V3  DDR4 2x16GB RECC Set Kit Support M.2 PCI-E NVME NGFF ATX Server
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  • $611.56 
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ASRock Rack GNRD8-2L2T CEB Server Motherboard Single Socket E2 (LGA 4710) Intel Xeon 6700E-series Dual 10GbE
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ASRock Rack
Open Box ASRock Rack GNRD8-2L2T CEB Server Motherboard Single Socket E2 (LGA 4710) Intel Xeon 6700E-series Dual 10GbE
  • Brand: AsRock Rack
  • CPU Type: Supports Intel Xeon 6700E-series processors
  • Number of Processor Support: 1
  • Memory Slots: 8 x DDR5 288-pin
  • Model #: GNRD8-2L2T/PTY
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  • $599.99 
  • $10.46 Shipping
SUPERMICRO MBD-X13SAZ-F-O Micro ATX Server Motherboard LGA 1700 Intel R680E
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SUPERMICRO MBD-X13SAZ-F-O Micro ATX Server Motherboard LGA 1700 Intel R680E
  • Brand: SUPERMICRO
  • CPU Socket Type: LGA 1700
  • CPU Type: Supports 12th Generation Intel Core i9/Core i7/Core i5/Core i3/Pentium/Celeron Processor
  • North Bridge: Intel R680E
  • Model #: MBD-X13SAZ-F-O
ASRock Rack Server Motherboard W880D4ID-2Q Deep mini-ITX Single Socket LGA 1851 Intel Core Ultra Desktop Processors (Series 2) Dual SFP28
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ASRock Rack
ASRock Rack Server Motherboard W880D4ID-2Q Deep mini-ITX Single Socket LGA 1851 Intel Core Ultra Desktop Processors (Series 2) Dual SFP28
  • Brand: ASRock
  • CPU Socket Type: LGA 1851
  • CPU Type: Intel Core Ultra Processors (Series 2)
  • Number of Processor Support: 1
  • Model #: W880D4ID-2Q
HFG24 Dell PE R430/530V1  Motherboard
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DELL
Refurbished HFG24 Dell PE R430/530V1 Motherboard
  • Brand: DELL
  • Model: HFG24
  • Model #: 011110367037
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  • $599.00 
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AsRock Rack ROMED4ID-2T Proprietary (Deep mini-ITX) Server Motherboard Socket SP3
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AsRock Rack ROMED4ID-2T Proprietary (Deep mini-ITX) Server Motherboard Socket SP3
  • Brand: AsRock Rack
  • CPU Socket Type: Socket SP3
  • CPU Type: Supports AMD EPYC 7003 (with AMD 3D V-Cache Technology*) / 7002 Series Processors *A BIOS update is required to support AMD EPYC 7003 series processors with AMD 3D V-Cache Technology
  • Number of DDR4 Slots: 4 x 288-pin
  • Model #: ROMED4ID-2T
  • $575.47 - $597.83
GIGABYTE MD72-HB3 Extended ATX Server Motherboard Dual Socket P+ Intel C621A
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GIGABYTE
Open Box GIGABYTE MD72-HB3 Extended ATX Server Motherboard Dual Socket P+ Intel C621A
  • Brand: GIGABYTE
  • CPU Socket Type: Dual Socket P+
  • CPU Type: Supports 3rd Generation Intel Xeon Scalable Processors
  • North Bridge: Intel C621A
  • Model #: MD72-HB3
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  • $584.99 
  • $11.62 Shipping
GIGABYTE MU72-SU0 ATX Server Motherboard Socket P+ Intel C621A
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GIGABYTE
GIGABYTE MU72-SU0 ATX Server Motherboard Socket P+ Intel C621A

OUT OF STOCK

  • Brand: GIGABYTE
  • CPU Socket Type: Socket P+
  • CPU Type: Supports 3rd Gen Intel Xeon Scalable Processors Supports Intel Xeon Platinum / Xeon Gold / Xeon Silver Processors
  • North Bridge: Intel C621A
  • Model #: MU72-SU0

Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP