Graphics cards need specific connections on a motherboard like PCI express in order to work. There are also specific PCI express slots needed in order to fully use the power of certain graphics cards. Most modern graphics cards and motherboards are compatible with one another, though there are edge cases with extremely large or power-hungry GPUs that won’t work with certain motherboards. Checking the specifications for your motherboard and the graphics card will help you understand if you have any compatibility issues.
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