Question 1

Is this compatible with the Synology DS918+ NAS system?

Accepted Answer

Yes I have them in my 918+ and they are working great, over months.
You can Google Synology hard drive compatibility list to see full list. Pick the NAS class hard drive filter to see the red series.

Question 2

I see this is NAS optimized but can it be used like a regular hard drive in your desktop?

Accepted Answer

Of course. It is a normal hard drive in functionality. It's just designed to operate at a lower temperature and draw less power when constantly run making them ideal for multi-drive storage arrays. However, for the money, it makes more sense to buy a WD Black for normal drive use. Similar price, but better performance

Question 3

Can I use this to replace a WD red NAS 5400 RPM drive in a MyCloudEX2Uldra NAS in a RAID 1 configura?

Accepted Answer

Yes you can.  I would replace all drives with Red Plus or Red Pro drives as the basic Red drives are WMR (shingled) and have no place in any raid enclosure imho.  Please see: nasmaster dot com wd-red-vs-red-plus-vs-red-pro-nas-hdd  I only use the WD Red Pro drives due to speed, warranty, rated workload, and excellent price when on sale.

Question 4

Is this a Retail or OEM version of the drive?

Accepted Answer

OEM. It comes in a brown non-retail box.

Question 5

Can this HD 6T|WD WD6003FFBX hard drive operate 24/7?

Accepted Answer

The WD Red Pro hard drive is designed for enterprise NAS systems and supports up to 300TB/year workload rate, indicating it is suitable for continuous operation.

Question 6

Can I use this as a replacement for a WD NAS Red 5400 RPM drive in a MycloudEX2Ultra NAS?

Accepted Answer

It is working in a Synology DiskStation DS918+. I'm assuming something similar to NAS.

Question 7

Shingled or non shingled?

Accepted Answer

The WD Red Pro WD6003FFBX 6TB 7200 RPM 256MB Cache SATA 6.0Gb/s 3.5" Internal Hard Drive is a non-shingled drive.

Question 8

Are all WD Red Pro 7200 RPM 256MB Cache Internal Hard Drives compatible with the WD 2100 PRO and 4100Pro NAS servers?

Accepted Answer

Unfortunately, the answer to your question is a negative.  According to the WD compatibility list for both models, only the WD4001FFSX (4 TB) & WD8001FFSX (8 TB) are compatible.

Features	Available in large capacities with support for 1-24 bays Enhanced reliability with 3D Active Balance Plus technology and error recovery controls with NASware 3.0 technology Extended drive testing to ensure each drive is tested for extended reliable operation Vibration & Shock protection
Usage	Enterprise NAS Hard Drives

Form Factor	3.5"
Height (maximum)	26.10mm
Width (maximum)	101.60mm
Length (maximum)	147.00mm

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Interface	SATA 6.0Gb/s
Capacity	6TB
NAND Flash Memory Type	Hard Drive
RPM	7200 RPM
Cache	256MB

Model
Brand	WD
Series	Red Pro
Model	WD6003FFBX

Item#: 9SIC7XHM1F1537