What liquid coolers can I use for the ASUS Prime X299-Deluxe LGA 2066 Intel X299 SATA 6Gb/s USB 3.1 ATX Intel Motherboard?

You can use any Liquid cooler's that have support for Socket 2011-V3 (X99), it's the same mounting specs. It just all depends on if you're going to just use it as is or if you plan on overclocking etc.

are the mounting holes with x299 the same for cooling solutions from x99 or are they slightly different like am4 was from am3?

From what I have read any cooler compatible with LGA2011/2011-v3 should work on LGA2066 however Intel is recommending Liquid coolers due to the high thermal output of the new CPUs.

Is the TPM installed or do I need to buy a module. If Not installed, where does it plug in?

I believe its already installed. I am running it and Windows has a driver installed for it.

Will this work on a Case that only has USB 2 and/or 3 on the front panel? What I want to know is if I plug my front panel USB 2/3 into the 3.1 gen 2 will it still operate or do I need some sort of adapter?

There is only one USB2 plug on the board so you could use that with the front plugs. There are two USB3 plugs on the board - one can be used for the front panel if they are USB 3.

What features make this board worth $180 more than the "non-deluxe" version?

I wondered the same thing, and decided to go with this board of the Prime X299-A. The cost difference is a couple things. This board has the onboard OLED display. Also this comes with both a fan extension board that allows for an additional 3 4pin PWM fans, and 3 Temp sensors. The board also comes with an PCIe Thunderbolt and USB-C card. This card adds both the latest version of thunderbolt and two more USB 3.1 ports, one being USB-C.

Can u boot off M.2 NVMe X4 same as x99 deluxe. and how much is SLI faster in FPS , is it worth $1500?

Yes, you can boot from and m.2 nvme. I don't think SLI is worth it for 1500 for me at least. Depends on you really, i'd normally go with the best single card i could afford. 1080ti should be good enough. Unless youre running 4k and want higher refresh rates.

Could I get a recomendation for a case that will fit this MB and 2 EVGA GeForce GTX 1080 Ti SC2 HYBRID GAMING, 11G-P4-6598-KR, 11GB GDDR5X, HYBRID & LED, iCX Technology - 9?

I happen to be quite fond of the Corsair Obsidian Series 750D.

does this motherboard is compatible with iCore 9?

Yes, this model compatible with the Intel core i9 processors.

can this MB support front usb c?

No, this model does not support front usb c.

Are all the features of this motherboard supported in linux (Ubuntu) ?

I don't see why not. The hardware is not software contingent. This is one smokin hot board especially if you install 128gb of Corsair 3200 ram and 2 Samsung 980 Pro M.2 drives as your primary RAID 0 boot drives. I swear it's nearly instant boot!

GIGABYTE Gaming Radeon RX 9070 XT 16GB GDDR6 PCI Express 5.0 x16 ATX Graphics Card GV-R9070XTGAMING OC-16GD

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ASUS Prime X299-Deluxe LGA 2066 Intel X299 USB 3.1 ATX Intel Motherboard

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Option: Prime X299-Deluxe

Prime X299-A
Prime X299-A II
Prime X299-Deluxe
Prime X299-Deluxe II
Prime X299 Edition 30
ROG RAMPAGE VI EXTRME OMEGA
ROG Strix X299-E Gaming
ROG Strix X299-E Gaming II
TUF X299 Mark 1
TUF X299 Mark 2
WS X299 PRO
WS X299 PRO/SE
WS X299 SAGE

Designed for 7th generation LGA2066 socket Intel Core X-Series processors to maximize connectivity and speed with U.2 port, dual M.2, Thunderbolt EX 3, front panel USB 3.1, onboard 802.11AC/AD WIFI, Intel VROC and Intel Optane Memory compatibility
5-Way Optimization with Auto-Tuning and FanXpert 4 automatically tailors overclocking profiles to your unique build for maximum OC performance and dynamic system cooling
SafeSlot (3X) features an injection molding process that integrates metal framing for a stronger, firmly anchored PCIe slot built for heavyweight GPUs
Unmatched Personalization with ASUS exclusive AURA Sync RGB lighting, additional RGB header and 3D-printing mounts to customize your build
Industry-leading 8-channel HD audio enhanced by ASUS exclusive Realtek S1220A featuring Crystal Sound 3 and driven by Japanese capacitors for warm, immersive sound

🔥Don't forget your OS, we have Windows 11 OEM, Download and USB versions available

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PRIME X299-DELUXE,ATX,Intel Core X-Series on LGA 2066 Socket,Intel X299, 8 x DIM

Model
Brand	ASUS
Model	Prime X299-Deluxe

Supported CPU
CPU Socket Type	LGA 2066
CPU Type	Core X series (LGA2066)
Supported CPU Technologies	The Intel Turbo Boost Max Technology 3.0 support depends on the CPU types

Chipsets
Chipset	Intel X299

Onboard Video
Onboard Video Chipset	None

Memory
Number of Memory Slots	Core X-series Processors (6-core above): 8 x 288pin Core X-series Processors (4-core): 4 x 288pin
Memory Standard	DDR4 4133(O.C.)/ 4000(O.C.)/ 3600(O.C.)/ 2666/ 2400/ 2133 ** Refer to www.asus.com for the Memory QVL (Qualified Vendors Lists). * Hyper DIMM support is subject to the physical characteristics of individual CPUs.
Maximum Memory Supported	Core X-series Processors (6-core above): 8 x DIMM, Max. 128GB Core X-series Processors (4-core): 4 x DIMM, Max. 64GB

Expansion Slots
PCI Express 3.0 x16	44-Lane CPU- 3 x PCIe 3.0/2.0 x16 (x16, x16/x16, x16/x16/x8) 1 x PCIe 3.0/2.0 x16 (max at x4 mode) 1 28-Lane CPU- 2 x PCIe 3.0/2.0 x16 (x16, x16/x8) 2 x PCIe 3.0/2.0 x16 (max at x4 mode) 1 16-Lane CPU- 2 x PCIe 3.0/2.0 x16 (x16 or dual x8) 2 x PCIe 3.0/2.0 x16 (max at x2 mode) *1 1. PCIEX16_4 shares bandwidth with SATA6G_5 & STATA6G_6 when using 28-lane & 16-lane CPUs. 1. PCIEX16_2 shares bandwidth with USB 3.1 Gen 2 front panel connector when using 16-lane CPUs. 1. PCIEX16_2 max. at x4 mode when using 44 & 28 lane CPUs, only compatible with PCIe x1 & x4 devices, PCIEX16_4 max. at x2 mode in 44-lane & 28-lane CPUs. 1. PCIEX16_2 max. at x1 mode & PCIEX16_4 max. at x2 mode in 16-lane CPUs.
PCI Express x1	2 x PCIe 3.0/2.0 x1 *2 2. PCIEX1_1 shares bandwidth with Wi-Fi 802.11 ad. It is disabled by default. PCIEX1_2 shares bandwidth with SATA6G_7. It is disabled by default.

Storage Devices
Serial ATA (SATA)	7 x SATA 6Gb/s port(s)*4 4. The SATA6G_7 shares bandwidth with PCIEX1_2. SATA6G_5 & SATA6G_6 shares bandwidth with PCIEX16_4 when using 28-lane & 16-lane CPU.
M.2	1 x M.2 x4 Socket 3, with M key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 x4 mode) 1 x M.2 x4 Socket 3, with M key, type 2242/2260/2280/22110 storage devices support (PCIE 3.0 x4 mode)*3 1 x U.2 port 3. The M.2_2 socket shares bandwidth with U.2 port. Adjust BIOS settings to use U.2 device.
Intel Optane Ready	Yes
SATA RAID	0/1/5/10

Onboard Audio
Audio Chipset	Realtek S1220A High Definition Audio CODEC
Audio Channels	8 Channels

Onboard LAN
LAN Chipset	Intel I219-V
Second LAN Chipset	Intel I211-AT
Max LAN Speed	2 x 1Gbps
Wireless LAN	Wi-Fi 802.11 a/b/g/n/ac + WiGig 802.11 ad*5 Supports MU-MIMO Supports dual band frequency 2.4/5 GHz + 60 GHz Up to 4600 Mbps transfer speed 5. Wi-Fi 802.11 ad shares bandwidth with PCIEX1_1. If a device is detected in PCIEX1_1, PCIEX1_1 will be enabled and Wi-Fi 802.11 ad will be disabled (Wi-Fi 802.11 a/b/g/n/ac is still enabled). Wi-Fi 802.11 ad (WiGig) is only available in certified countries.
Bluetooth	Bluetooth 4.1

Rear Panel Ports
RJ45	2 x RJ45
USB 3.1	3 x USB 3.1 Gen 2 Type-A 4 x USB 3.1 Gen 1
USB 1.1/2.0	4 x USB 2.0 (one port can be switched to USB BIOS Flashback)
USB Type-C	1 x USB 3.1 Gen 2 USB Type-C
S/PDIF Out	1 x Optical
Audio Ports	5 Ports
Antenna Connectors	1 x ASUS Wi-Fi GO! module (Wi-Fi 802.11 a/b/g/n/ac + WiGig 802.11 ad and Bluetooth v4.1)

Internal I/O Connectors
Onboard USB	1 x USB 3.1 Gen 2 front 1 x USB 3.1 Gen 1 connector(s) support(s) additional 2 USB 3.1 Gen 1 port(s) 2 x USB 2.0 connector(s) support(s) additional 4 USB 2.0 port(s)
Other Connectors	1 x Aura Addressable Strip Header(s) 1 x AAFP connector 1 x Aura RGB Strip Header 1 x M.2_FAN connector 1 x VROC_HW_Key 1 x CPU Fan connector(s) 1 x CPU OPT Fan connector(s) 2 x Chassis Fan connector(s) 1 x W_PUMP+ connector 1 x AIO_PUMP connector 1 x Thunderbolt header(s) 1 x EZ XMP switch 1 x System panel(s) (Q-Connector) (Chassis intrusion header is inbuilt) 1 x 5-pin EXT_FAN (Extension Fan) connector 1 x MemOK! button(s) 1 x Thermal sensor connector(s) 1 x Power-on button(s) 1 x Reset button(s) 1 x Clear CMOS button(s)

Physical Spec
Form Factor	ATX
LED Lighting	RGB
Dimensions (W x L)	12.0" x 9.6"
Power Pin	1 x 24-pin EATX Power connector(s) 1 x 8-pin ATX 12V Power connector(s) 1 x 4-pin ATX 12V Power connector(s)

Features
Features	Special Features: OC Design - ASUS PRO Clock II Technology 5-Way Optimization by Dual Intelligent Processors 5 - 5-Way Optimization tuning key perfectly consolidates TPU, EPU, DIGI+ VRM, Fan Xpert 4, and Turbo Core App ASUS 5X Protection III: - ASUS SafeSlot Core: Fortified PCIe Slot prevents damage - ASUS LANGuard: Protects against LAN surges, lightning strikes and static-electricity discharges! - ASUS Overvoltage Protection: World-class circuit-protecting power design - ASUS Stainless-Steel Back I/O: 3X corrosion-resistance for greater durability! - ASUS DIGI+ VRM: 8 Phase digital power design - ASUS Enhanced DRAM Overcurrent Protection - Short circuit damage prevention - ASUS ESD Guards - Enhanced ESD protection AURA: - Aura RGB Strip Headers - Aura Lighting Effects Synchronization with compatible ASUS ROG devices - Aura Addressable Strip Header(s) ASUS Exclusive Features: - USB BIOS Flashback - MemOK! - AI Suite 3 - Ai Charger - Onboard Button: Power/Reset - ASUS UEFI BIOS EZ Mode featuring friendly graphics user interface - Turbo LAN File Transfer - Cloud GO! - File Transfer ASUS Quiet Thermal Solution: - Stylish Fanless Design with M.2 Heat-sink solution ASUS EZ DIY: - ASUS EZ Flash 3 - ASUS USB BIOS Flashback - ASUS UEFI BIOS EZ Mode - Multi-language BIOS ASUS Q-Design: - ASUS Q-Shield - ASUS Q-Code - ASUS Q-LED (CPU, DRAM, VGA, Boot Device LED, HDD LED) - ASUS Q-Slot - ASUS Q-DIMM - ASUS Q-Connector M.2 and U.2 Onboard (The Latest Transfer Technology with up to 32Gb/s Data-transfer Speeds for M.2 and U.2) BIOS: 128MB Flash ROM, UEFI AMI BIOS, PnP, DMI3.0, WfM2.0, SM BIOS 3.0, ACPI 6.0, Multi-language BIOS, ASUS EZ Flash 3, CrashFree BIOS 3, F11 EZ Tuning Wizard, F6 Qfan Control, F3 My Favorites, Last Modified log, F12 PrintScreen and ASUS DRAM SPD (Serial Presence Detect) memory information Operating System: Windows 10 64-bit

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First Listed on Newegg	May 29, 2026

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