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H11SSL-C Motherboard ATX Single Socket SP3  EPYC 7002/7001 Retail Box
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ASUS Pro WS WRX90E-SAGE SE EEB Workstation motherboard, AMD Ryzen™ Threadripper™ PRO 7000 WX-Series Processors, ECC R-DIMM DDR5, 32 power-stage,7xPCIe 5.0 x 16, PCIe 5.0 M.2, 10 Gb and 2.5 Gb LAN
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ASUS Pro WS WRX90E-SAGE SE EEB Workstation motherboard, AMD Ryzen™ Threadripper™ PRO 7000 WX-Series Processors, ECC R-DIMM DDR5, 32 power-stage,7xPCIe 5.0 x 16, PCIe 5.0 M.2, 10 Gb and 2.5 Gb LAN
  • Brand: ASUS
  • CPU Socket Type: Socket sTR5
  • CPU Type: AMD Ryzen Threadripper PRO 7000 Series / AMD Ryzen Threadripper PRO 9000 Series
  • North Bridge: AMD WRX90
  • Model #: Pro WS WRX90E-SAGE SE
Dell Motherboard For EMC Poweredge R750 Server 2x FCLGA4189 216NK
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For     PRIMERY TX200 S4 MCL-D2509 Motherboard D2509-A11
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For X3400 X3500 server main motherboard 42C1549 43W5176 44R5619
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Dell Motherboard For EMC Poweredge R750 Server 2x FCLGA4189 V3GRK
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  • $2,099.00 
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Asrock Rack Ampere Altra Bundle ALTRAD8UD-1L2T Deep Micro-ATX Server Motherboard Single Socket (LGA 4926) with Ampere Altra M128-26 128 cores & 2U passive cooler, Dual 10G - Integrated by Asrock Rack
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Asrock Rack Ampere Altra Bundle ALTRAD8UD-1L2T Deep Micro-ATX Server Motherboard Single Socket (LGA 4926) with Ampere Altra M128-26 128 cores & 2U passive cooler, Dual 10G - Integrated by Asrock Rack

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  • Brand: AsRock Rack
  • Part Number: ALTRAD8UD-1L2T-M128-26
  • CPU Socket Type: Single Socket (LGA 4926)
  • CPU Type: Ampere Altra Max/Ampere Altra processors
  • Model #: ALTRAD8UD-1L2T-M128-26
  • $2,999.00
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ASRock WRX90 WS EVO SATA 6Gb/s DDR5  AMD Ryzen Threadripper PRO 7 x PCIe 5.0 x16 Slots 2 x 10 Gigabit LAN Motherboards - AMD
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ASRock WRX90 WS EVO SATA 6Gb/s DDR5 AMD Ryzen Threadripper PRO 7 x PCIe 5.0 x16 Slots 2 x 10 Gigabit LAN Motherboards - AMD
  • Brand: ASRock
  • CPU Socket Type: Socket sTR5
  • CPU Type: Supports AMD Ryzen Threadripper PRO 9000/7000 WX-Series Processors
  • North Bridge: AMD WRX90
  • Model #: WRX90 WS EVO
ASUS Pro WS WRX80E-SAGE SE WiFi II AMD WRX80 Extended-ATX
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ASUS
ASUS Pro WS WRX80E-SAGE SE WiFi II AMD WRX80 Extended-ATX
  • CPU Socket Type: sWRX8
  • Model #: Threadripper24
X10SDV-6C-TLN4F Motherboard Mini-ITX SoC Xeon D-1528 6-Core, Single Socket FCBGA 1667
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For U45/U25 workstation main motherboard 375-3277 375-3278 375-3552 375-3553
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For   Tower Server Think System ST550 Main Board 00MX682
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ASRock Rack D1749NTD4U-4Q Micro-ATX SoC Server Motherboard Intel® Xeon® D-1749NT processor PCIe4.0 4 SFP28 (Up to 25GbE)
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ASRock Rack D1749NTD4U-4Q Micro-ATX SoC Server Motherboard Intel® Xeon® D-1749NT processor PCIe4.0 4 SFP28 (Up to 25GbE)

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  • Brand: AsRock Rack
  • CPU Type: Intel Xeon D-1749NT
  • Number of Processor Support: 1
  • CPU Features: Thermal Design Power Up to 90W
  • Model #: D1749NTD4U-4Q
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M11SDV-8C+-LN4F Motherboard Mini-ITX Embedded  EPYC 3251 SoC Processor
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For 4559-11 Medical System 501-4559 With CPU Memory motherboard
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GIGABYTE MC62-G40 AMD Ryzen Threadripper PRO Workstation Board with AMD Threadropper Pro 5965WX Bundle Deal,24-core, 48-Thread, Processor Integrated by GIGABYTE
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GIGABYTE MC62-G40 AMD Ryzen Threadripper PRO Workstation Board with AMD Threadropper Pro 5965WX Bundle Deal,24-core, 48-Thread, Processor Integrated by GIGABYTE
  • Brand: GIGABYTE
  • CPU Socket Type: Socket sWRX8
  • CPU Type: Supports AMD Ryzen Threadripper PRO 5000WX Series Processors Supports AMD Ryzen Threadripper PRO 3000WX Series Processors
  • Number of Processor Support: 1
  • Model #: MC62-G40-5965WX01
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For XW9300 server main motherboard 381863-001 374254-002 409665-001
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ASUS Pro WS TRX50-SAGE WIFI A workstation motherboard
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ASUS Pro WS TRX50-SAGE WIFI A workstation motherboard
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  • CPU Socket Type: Socket sTR5
  • CPU Type: AMD Ryzen Threadripper 7000 Series / AMD Ryzen Threadripper 9000 Series / AMD Ryzen Threadripper PRO 7000 Series / AMD Ryzen Threadripper PRO 9000 Series
  • North Bridge: AMD TRX50
  • Model #: Pro WS TRX50-SAGE WIFI A
TYAN Combo Deal, S8030GM2NE ATX Server Motherboard Installed AMD EPYC 7252, 8 Cores, 16 Threads, 3.2GHz, 120W. Factory Installed/Tested/Burn-in/Shipped
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TYAN Combo Deal, S8030GM2NE ATX Server Motherboard Installed AMD EPYC 7252, 8 Cores, 16 Threads, 3.2GHz, 120W. Factory Installed/Tested/Burn-in/Shipped
  • Brand: TYAN
  • CPU Socket Type: Socket SP3
  • CPU Type: Supports AMD EPYC 7002/7003 (with AMD 3D V-Cache Technology) Series Processor
  • Number of Processor Support: 1
  • Model #: S8030GM2NE-7252
For H6CZ02 GGKK7250007J J50750-103 KBL-S EV/CRB equipment motherboard
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For NET-2814 CA688A VER COO Server Dual Motherboard NET-2814
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For   Micro C2SBC-RSYS-QZ2 775-Pin QZ35Q Medical Device Motherboard
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ASUS PRO WS WRX90E-SAGE SE AMD WRX90 Threadripper PRO, 2 x Intel X7100-AT2 dual 10Gb + 1x RTL8211F 1Gb/ USB 3.2 Gen2 x6,
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For TX200 S5 W26361-W1762-Z4-05-36 D2709-A13 motherboard
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For   Z11PA-U12 LGA 3647 Server Motherboard C621 Chipset
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Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP