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HPE Proliant DL360 Gen11 Motherboard System Board P42353-001 P53214-001
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  • $2,500.00 –
  • $18.00 Shipping
X11SAT Motherboard ATX For Up To Xeon E3-1200v5
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H11SSL-C Motherboard ATX Single Socket SP3  EPYC 7002/7001 Retail Box
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ASUS Pro WS WRX80E-SAGE SE WIFI AMD Threadripper Pro EATX workstation motherboard (PCIe 4.0, ASMB9-iKVM, 2x10Gb LAN, 7xPCIe 4.0 X16 slots, 3xM.2,2xU.2 ports, 11 USB 3.2 Gen 2 ports,8-channel DDR4 ECC)
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ASUS Pro WS WRX80E-SAGE SE WIFI AMD Threadripper Pro EATX workstation motherboard (PCIe 4.0, ASMB9-iKVM, 2x10Gb LAN, 7xPCIe 4.0 X16 slots, 3xM.2,2xU.2 ports, 11 USB 3.2 Gen 2 ports,8-channel DDR4 ECC)
  • Brand: ASUS
  • CPU Socket Type: Socket sWRX8
  • CPU Type: AMD Ryzen Threadripper PRO 5000 Series / AMD Ryzen Threadripper PRO 7000 Series / AMD Ryzen Threadripper PRO 9000 Series
  • North Bridge: AMD WRX80
  • Model #: Pro WS WRX80E-SAGE S
ASUS Pro WS W890E-SAGE SE Intel W890 (LGA 4710-2) EEB workstation motherboard, PCIe 5.0 x16, M.2, MCIO, SlimSAS, 2x 10Gb LAN, Server-grade Remote Management, 16+(2+2)+1+2 stages, USB4, USB Type-C
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ASUS
ASUS Pro WS W890E-SAGE SE Intel W890 (LGA 4710-2) EEB workstation motherboard, PCIe 5.0 x16, M.2, MCIO, SlimSAS, 2x 10Gb LAN, Server-grade Remote Management, 16+(2+2)+1+2 stages, USB4, USB Type-C
  • Brand: ASUS
  • M.2: Intel Xeon 690/670/650 Series Processors** M.2_1 slot (Key M), type 2242/2260/2280/22110 (supports PCIe 5.0 x4 mode) M.2_2 slot (Key M), type 2242/2260/2280/22110 (supports PCIe 5.0 x4 mode) M.2_3 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode) M.2_4 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode) MCIO connector (supports PCIe 5.0 x8, and runs at x4/x4) Intel Xeon 630 Series Processor** M.2_1 slot (Key M), type 2242/2260/2280/22110 (supports PCIe 5.0 x4 mode) M.2_2 slot (Key M), type 2242/2260/2280/22110 (supports PCIe 5.0 x4 mode) M.2_3 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode) M.2_4 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode)
  • Serial ATA (SATA): 4 x SATA 6Gb/s
  • CPU Socket Type: LGA 4710-2
  • Model #: Pro WS W890E-SAGE SE
GIGABYTE MC62-G40 AMD Ryzen Threadripper PRO Workstation Board
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GIGABYTE
GIGABYTE MC62-G40 AMD Ryzen Threadripper PRO Workstation Board
  • Brand: GIGABYTE
  • CPU Socket Type: Socket sWRX8
  • CPU Type: Supports AMD Ryzen Threadripper PRO 5000WX Series Processors Supports AMD Ryzen Threadripper PRO 3000WX Series Processors
  • Number of Processor Support: 1
  • Model #: MC62-G40
Dell Motherboard For EMC Poweredge R750 Server 2x FCLGA4189 216NK
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  • $2,199.00 –
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For     PRIMERY TX200 S4 MCL-D2509 Motherboard D2509-A11
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  • $2,198.90 –
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For X3400 X3500 server main motherboard 42C1549 43W5176 44R5619
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  • $2,206.00 –
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Dell Motherboard For EMC Poweredge R750 Server 2x FCLGA4189 V3GRK
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  • $2,099.00 –
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For U45/U25 workstation main motherboard 375-3277 375-3278 375-3552 375-3553
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  • $2,060.00 –
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Asrock Rack ROMED8-2T Server Motherboard AMD EPYC 7003 (with AMD 3D V-Cache Technology)/7002 series processors SP3 (LGA 4094) Dual 10GbE
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Asrock Rack ROMED8-2T Server Motherboard AMD EPYC 7003 (with AMD 3D V-Cache Technology)/7002 series processors SP3 (LGA 4094) Dual 10GbE
  • Brand: AsRock Rack
  • CPU Socket Type: Socket SP3
  • CPU Type: Supports AMD EPYC 7003 (with AMD 3D V-Cache Technology*) / 7002 Series Processors *A BIOS update is required to support AMD EPYC 7003 series processors with AMD 3D V-Cache Technology
  • Number of Processor Support: 1
  • Model #: ROMED8-2T
For   Tower Server Think System ST550 Main Board 00MX682
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  • $1,978.90 –
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M11SDV-8C+-LN4F Motherboard Mini-ITX Embedded  EPYC 3251 SoC Processor
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*LENOVO 7Z23 SR670 V2 SYSTEM BOARD ICE LAKE EMBEDDED TPM 02JK727
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  • $1,969.00 –
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*THINKSYSTEM TYPE 7D9RSR675 V3 SYSTEM BOARD WITH BATTERY
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  • $1,969.00 –
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*THINKSYSTEM TYPE 7D9RSR675 V3 SYSTEM BOARD WITH BATTERY
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  • $1,969.00 –
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THINKSYSTEM TYPE 7D9RSR675 V3 SYSTEM BOARD WITH BATTERY
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  • $1,969.00 –
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For 4559-11 Medical System 501-4559 With CPU Memory motherboard
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  • $1,912.00 –
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ASUS PRO WS WRX90E-SAGE SE AMD WRX90 Threadripper PRO, 2 x Intel X7100-AT2 dual 10Gb + 1x RTL8211F 1Gb/ USB 3.2 Gen2 x6,
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  • $1,895.99 –
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For XW9300 server main motherboard 381863-001 374254-002 409665-001
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  • $1,866.00 –
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GIGABYTE MZ73-LM1 Server Motherboard - AMD EPYC™ 9005/9004 - E-ATX DP PCIe Gen4 cTDP 400W
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GIGABYTE
GIGABYTE MZ73-LM1 Server Motherboard - AMD EPYC™ 9005/9004 - E-ATX DP PCIe Gen4 cTDP 400W
  • Brand: GIGABYTE
  • Part Number: MZ73-LM1
  • CPU Socket Type: 2 x LGA 6096
  • CPU Type: AMD EPYC 9004 Series
  • Model #: MZ73-LM1
GIGABYTE MZ73-LM0 Rev. 3.x Server Motherboard - AMD EPYC™ 9005/9004 - E-ATX DP PCIe Gen5 cTDP 400W
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GIGABYTE
GIGABYTE MZ73-LM0 Rev. 3.x Server Motherboard - AMD EPYC™ 9005/9004 - E-ATX DP PCIe Gen5 cTDP 400W
  • Brand: GIGABYTE
  • CPU Socket Type: Socket SP5
  • CPU Type: AMD EPYC 9004 Series / AMD EPYC 9005 Series
  • Number of Processor Support: 2
  • Model #: MZ73-LM0
TYAN Combo Deal, S8030GM2NE ATX Server Motherboard Installed AMD EPYC 7252, 8 Cores, 16 Threads, 3.2GHz, 120W. Factory Installed/Tested/Burn-in/Shipped
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TYAN Combo Deal, S8030GM2NE ATX Server Motherboard Installed AMD EPYC 7252, 8 Cores, 16 Threads, 3.2GHz, 120W. Factory Installed/Tested/Burn-in/Shipped
  • Brand: TYAN
  • CPU Socket Type: Socket SP3
  • CPU Type: Supports AMD EPYC 7002/7003 (with AMD 3D V-Cache Technology) Series Processor
  • Number of Processor Support: 1
  • Model #: S8030GM2NE-7252
For H6CZ02 GGKK7250007J J50750-103 KBL-S EV/CRB equipment motherboard
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For NET-2814 CA688A VER COO Server Dual Motherboard NET-2814
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  • $1,758.90 –
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For M720 main motherboard D3228-A14 15
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  • $1,766.00 –
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Server motherboards play a pivotal role in facilitating efficient communication between CPUs and other server hardware. While functionally similar to traditional computer motherboards, server motherboards are specifically designed to handle more intensive workloads, higher temperatures, and environmental stress typical in data centers and high-density IT network environments. Selecting the appropriate server motherboard significantly impacts server performance, reliability, and scalability.

Optimize Your Space with the Right Server Motherboard

Choosing the appropriate form factor is crucial when selecting a server motherboard. Popular server motherboard form factors include ATX, Mini-ITX, Micro-ATX, and specialized boards such as Mini-ITX motherboards with 10GbE or dual LAN support. An ATX motherboard offers compatibility with multiple redundant power supplies and expansive hardware support, making it ideal for high-capacity applications. In contrast, Mini-ITX and Micro-ATX motherboards, with their compact designs, are perfect for environments where space optimization is vital, such as NAS servers or densely packed data centers. Be sure to consider the rack type and required components when choosing the right form factor for your server chassis

Maximize Compute Power with Flexible CPU Compatibility

Server motherboard selection directly influences your choice of CPUs. Whether you're configuring a workstation motherboard or a dedicated server motherboard, compatibility with CPUs such as AMD EPYC, Intel Xeon W, Ampere Altra, or Threadripper Pro is essential. Motherboards designed specifically for EPYC CPUs, such as EPYC 4005 , EPYC 4004, EPYC 7003, EPYC 9004, and EPYC 9005, offer robust compute performance and flexibility. Options like dual processor motherboards, dual AMD EPYC motherboards, or quad processor motherboards further enhance compute capability and scalability.

Motherboards featuring sockets such as AMD SP5 or AM5 provide extensive options for CPU combinations. Selecting an AMD EPYC motherboard or Intel-compatible dual Xeon motherboard enables cost-effective upgrades and ensures performance consistency across server deployments.You should be able to keep your motherboard in most cases.

Enhanced Storage and Memory Support

Server motherboards also dictate your server memory and storage solutions. ECC memory, crucial for error correction and reliability in servers, requires a compatible motherboard. Many server motherboards support both ECC and non-ECC memory, providing flexibility based on your performance and budget needs. Compatibility with specialized storage solutions like SAS motherboards also enhances storage efficiency and data throughput, critical in demanding IT environments.

Effective Cooling and Energy Efficiency

Cooling is a primary consideration when deploying servers. Efficient cooling reduces operational costs and minimizes system downtime due to overheating. Smaller form factors like Micro ITX often require enhanced cooling features integrated directly into the motherboard design. Selecting a motherboard with robust built-in cooling capabilities can significantly reduce cooling-related expenditures. Manufacturers such as Supermicro deliver server motherboards that incorporate advanced cooling technologies even in compact form factors, contributing to environmental sustainability and compliance with global energy standards.

FAQs about Server Motherboards

  • How do I choose the right form factor for my server chassis?

    Match your motherboard’s form factor (ATX, Micro-ATX, Mini-ITX) to both your rack or tower chassis and intended use. ATX fits larger chassis with multiple power supplies and expansion slots; Micro-ATX and Mini-ITX work best in compact NAS or blade-style chassis where space and airflow are at a premium.
  • What cooling features should I look for in a server motherboard?

    Look for integrated heatsinks on VRMs, reinforced fan headers, and support for chassis-level airflow designs. Boards from vendors like Supermicro often include fan-control profiles and thermal sensors to optimize cooling in dense rack environments.
  • Can I use non-ECC memory on a server motherboard?

    Only if the board explicitly supports it. Many server boards let you choose between ECC and non-ECC DIMMs—but to benefit from error-correcting features in critical workloads, always pair ECC memory with an ECC-capable motherboard.

Bestselling Server Motherboards Reviews:

John M.
9/16/2025 12:11:52 PM
A Cheaper and Better End State Workstation Configuration

“ The reason is that the board is most definitely designed to be a server motherboard. ”

GIGABYTE MH53-G40 Server Motherboard - AMD Ryzen™ Threadripper™ PRO 9000/7000 WX - E-ATX UP