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Kensington Pro Fit K75501WW Black 6 Buttons 1 x Wheel USB RF Wireless Ergo Vertical Mouse
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Kensington Pro Fit K75501WW Black 6 Buttons 1 x Wheel USB RF Wireless Ergo Vertical Mouse
  • Resolution (DPI): 1600 dpi
  • Power Supply: 1 x AA Battery
  • Distance: 66 ft.
  • Model #: K75501WW
HyperX Pulsefire Haste 2 Wired Gaming Mouse 53g 26000 DPI 6 buttons Mice White
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HP
HyperX Pulsefire Haste 2 Wired Gaming Mouse 53g 26000 DPI 6 buttons Mice White
  • Part Number: 6N0A8AA
  • Features: Lighting - RGB, Up to 26000 DPI, 6 Programmable Buttons
  • Model #: 6N0A8AA
HP 925 Ergonomic Vertical Mouse For Business Model 6H1A5AA
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Adesso iMouseE1 Vertical illuminated Ergonomic USB mouse
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Adesso iMouseE1 Vertical illuminated Ergonomic USB mouse
  • Resolution (DPI): 1600 dpi
  • Package Contents: iMouse E1 - Vertical Ergonomic Illuminated Mouse Quick Start Guide
  • Model #: iMouse E1
HP 715 Rechargeable Multi-Device Mouse
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HP
HP 715 Rechargeable Multi-Device Mouse
  • Brand: HP
  • Type: Wired / Wireless
  • Tracking Method: N/A
  • Part Number: 6E6F0AA#ABL
  • Model #: 6E6F0AA#ABL
Targus ErgoFlip EcoSmart Sustainable Ambidextrous Full-Size Mouse AMB586GL
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Lenovo Go Wireless Vertical Mouse - Optical - Wireless - 2.40 GHz - Storm Gray - USB Type A - 2400 dpi - Scroll Wheel - 6 Button(s) - 3 Programmable Button(s)
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Lenovo
Lenovo Go Wireless Vertical Mouse - Optical - Wireless - 2.40 GHz - Storm Gray - USB Type A - 2400 dpi - Scroll Wheel - 6 Button(s) - 3 Programmable Button(s)
  • Hand Orientation: Right Hand
  • Resolution (DPI): 3-level adjustable (default at 2400,1600,800)
  • Power Supply: 1 x AA Battery
  • Operating Time: Up to 12 months
  • Model #: 4Y51C33792
Mouse
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Mouse
  • Model #: iMouseS60B
iMouse T40 - Wireless Programmable Ergonomic Trackball Mouse
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iMouse T40 - Wireless Programmable Ergonomic Trackball Mouse
  • Hand Orientation: Both Hands
  • Resolution (DPI): 4800 dpi
  • Distance: Up to 30.0 Feet
  • Operating System Supported: Windows 2000 / XP / Vista / 7 / 8 / 10
  • Model #: iMouseT40
Lenovo Essential USB Mouse
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Lenovo
Lenovo Essential USB Mouse
  • Part Number: 4Y50R20863
  • Hand Orientation: Both Hands
  • Resolution (DPI): 1600 dpi
  • Operating System Supported: Windows 7, Windows 8, Windows 8.1, Windows 10, Windows 11
  • Model #: 4Y50R20863
ADESSO iMouse S60R Red 6 Buttons Tilt Wheel USB RF Wireless Optical Mouse
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ADESSO iMouse S60R Red 6 Buttons Tilt Wheel USB RF Wireless Optical Mouse
  • Hand Orientation: Right Hand
  • Resolution (DPI): 1600 dpi
  • Power Supply: 2 x AAA Batteries
  • Distance: Up to 30 feet
  • Model #: iMouseS60R
ADESSO IMOUSEE90 ADESSO 2.4GHZ WIRELESS ERGONOMIC VERTICAL MOUSE FOR LEFT-HANDERS, BACK & FORWARD
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HyperX Pulsefire Mat Gaming Mouse Pad 572Y5AA
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HP 410 Slim AHS BT Mouse 4M0X5AA#ABL Bluetooth Bluetooth Wireless Mouse
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  • $48.99
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  • $19.99 
  • Save: 59%
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Adesso iMouseE10 2.4 GHz RF wireless Vertical Ergonomic mouse with DPI switch button
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Adesso iMouseE10 2.4 GHz RF wireless Vertical Ergonomic mouse with DPI switch button
  • Resolution (DPI): 2000 dpi
  • Power Supply: AAA
  • Distance: Up to 30 feet
  • System Requirement: USB Port Operating Systems: Windows 8 Windows 7 Windows Vista Windows XP Windows 2000 Mac OS X and Above
  • Model #: IMOUSEE10
  • $39.99 - $51.19
Lenovo 600 Bluetooth Silent Mouse
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Lenovo 600 Bluetooth Silent Mouse
  • Hand Orientation: Both Hands
  • Resolution (DPI): 2400 dpi
  • Power Supply: 1 x AA Battery
  • Operating Time: Up to 12 months (may vary based on usage)
  • Model #: GY50X88832
Adesso iMouseM300W White bluetooth 3.0 low profile "sleek" feel, comfort design, Optical scroll mouse for Mac and Windows OS
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Adesso iMouseM300W White bluetooth 3.0 low profile "sleek" feel, comfort design, Optical scroll mouse for Mac and Windows OS
  • Resolution (DPI): 1000 dpi
  • Power Supply: 2 x AAA Batteries
  • Distance: Up to 30 feet
  • Operating System Supported: Windows 8/ 7/ Vista/ XP; Mac OS X 10.4 and above
  • Model #: IMOUSE M300W
Adesso Multi-Color 6-Button Gaming Mouse
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Adesso Multi-Color 6-Button Gaming Mouse
  • Resolution (DPI): 3200 dpi
  • Package Contents: Multi-Color 6-Button Gaming Mouse Quickstart Guide
  • Model #: IMOUSE X1
Adesso iMouse T50 - Wireless Programmable Ergonomic Trackball Mouse
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Adesso iMouse T50 - Wireless Programmable Ergonomic Trackball Mouse
  • Hand Orientation: Both Hands
  • Resolution (DPI): 4800 dpi
  • Power Supply: 2 x AAA Batteries
  • Distance: 30 ft.
  • Model #: IMOUSE T50
Kensington Presentation Pointer K33271WW
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Logitech M325S Wireless Mouse 910007522
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Logitech
Logitech M325S Wireless Mouse 910007522
  • Brand: Logitech
  • Type: see description
  • Model #:
Logitech (G) G502  HERO  Wired Gaming Mouse,    RGB with Weighted Macro Programming, 25600DPI, 11buttons,  Laptop Big Hand Mouse, for Windows® 7 or later/macOS 10.11 or later/ChromeOS, BLACK
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Logitech (G) G502 HERO Wired Gaming Mouse, RGB with Weighted Macro Programming, 25600DPI, 11buttons, Laptop Big Hand Mouse, for Windows® 7 or later/macOS 10.11 or later/ChromeOS, BLACK

Limited time offer, ends 01/30

  • Hand Orientation: Both Hands
  • Resolution (DPI): 25600 dpi
  • Version: G502 HERO WIRED
  • Operating System Supported: Windows XP/ Vista; Mac OS X 10.X +
  • Model #: 042 G502 HERO BLACK
Logitech M325S Wireless Mouse 910007527
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Logitech
Logitech M325S Wireless Mouse 910007527
  • Brand: Logitech
  • Type: see description
  • Model #:
Logitech M325S Wireless Mouse
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Logitech M185 Wireless Mouse, 2.4GHz with USB Mini Receiver, 12-Month Battery Life, 1000 DPI Optical Tracking, Ambidextrous, Compatible with PC, Mac, Laptop - Blue
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Logitech M185 Wireless Mouse, 2.4GHz with USB Mini Receiver, 12-Month Battery Life, 1000 DPI Optical Tracking, Ambidextrous, Compatible with PC, Mac, Laptop - Blue
  • Brand: LOGITECH - COMPUTER ACCESSORIES
  • Color: Blue
  • Type: Office Products
  • Features: Sold as 1 Each.
  • Model #: 910-003636

Computer mice often are the unsung heroes of the home and office computing world. While your PC probably shipped with a standard mouse, if you haven't upgraded it, it is unlikely that you're getting the most from your time online or gaming. Modern Bluetooth mice can offer a seamless, virtually lag-free experience, while models with multiple buttons make it easier to keep pace with some of the best gamers in the world while enhancing your word processing and graphic design work. Shape and size determine how the mouse feels in your hand, with some people preferring lightweight models and others preferring something with extra heft. Button layout and configuration can greatly influence your mouse experience.

Laser Mice Offer Precision Movement

Computer mice use laser or optical sensors to track movement. Laser models track up to 2,000 dots per inch (dpi) while optical mice only track approximately 600. Most home users don't need the precision of a laser, and optical versions are less expensive. Graphic designers, videographers and serious gamers benefit from laser tracking because the movements on screen more precisely mirror the movement of the mouse.

Enjoy Greater Flexibility With Configurable Buttons

Most computer mice include left and right buttons, as well as a tracker wheel in the middle. Advanced versions can include two or four side buttons, and allow the user to configure these buttons to their own settings. A simple use may be to perform the function of the back button on your browser. Gamers might map a series of commands to one of these buttons, allowing them to pull off a complex move in one press.

Improve Mobility With Wireless Mice

Wired mice connect to a PC using USB or the PS/2 port. You will use the PS/2 port to connect other input devices such as keyboards so consider your configuration and whether you have a spare port available. If not, opt for a USB connection. PCs typically come with an array of ports so that you can connect mice and other USB gadgets. You can buy additional hubs that expand a single port to give four or more connections and allow the addition of all your computer accessories. Even wireless mice, which eliminate wire snags and make it easier to move your input device around, still require a USB port to connect the wireless receiver. They also take batteries or include a charging dock or wire.

Travel Mice Are Useful for Small Hands

Most portable and Bluetooth mice are smaller than their full-bodied counterparts. This is so that they will more easily fit into the pockets of a laptop bag and take up less space. However, they also offer benefits to users with smaller hands. It is important that you can comfortably fit your hand around a mouse, ensuring that your fingers rest easily over the buttons, and the diminutive form of travel mice makes this possible, even for children's hands.

Bestselling Mouse Reviews:

Andrew S.
1/5/2026 5:42:10 PM
The better ergo mouse

“ Having used a wired "gaming" vertical mouse and a cheaper wireless rechargeable one, this is really where I should have started. ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite
Anonymous
12/25/2025 9:35:25 AM
Mouse fits so comfortably!

“ I have had this mouse for years and it finally wore out. ”

Logitech - M500s Advanced Wired Optical Mouse with Hyper-fast Scrolling & Tilt - Wired - Black 910-007476
Steven K.
11/21/2025 9:17:37 AM
Great Mouse

“ Overall I like this mouse better than the traditional flat mouse. ”

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black
Don M.
10/13/2025 2:14:10 PM
Comfortable, reliable, long-lasting solution for hand and wrist pain

“ I've been using the MX Vertical Mouse for 5 years now, and only had to replace the mouse once in that time (spilled drink, not a product issue). ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite
Jaime G.
10/10/2025 3:17:53 PM
A LIFE SAVER For Carpal Tunnel Syndrome

“ I love this mouse so much I bought a couple of spares in case it gets discontinued. ”

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black